Results 91 to 100 of about 19,512 (206)

Microrna profiling analysis of differences between the melanoma of young adults and older adults [PDF]

, 2010
Background This study represents the first attempt to perform a profiling analysis of the intergenerational differences in the microRNAs (miRNAs) of primary cutaneous melanocytic neoplasms in young adult and older age groups.
Drazen M Jukic, Uma N.M. Rao, Lori Kelly, Jihad S Skaf, Laura M Drogowski, John M Kirkwood, Monica C Panelli   +6 more
core   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

The NF1 somatic mutational landscape in sporadic human cancers [PDF]

, 2017
Background Neurofibromatosis type 1 (NF1: Online Mendelian Inheritance in Man (OMIM) #162200) is an autosomal dominantly inherited tumour predisposition syndrome.
Cooper, David Neil, Frayling, Ian Martin, Philpott, Charlotte, Tovell, Hannah, Upadhyaya, Meena   +4 more
core   +2 more sources

Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease—A Register‐Based Cohort Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Mucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart. Methods This register‐based cohort study reviews head and neck melanomas at Helsinki University Hospital, Finland, from 2002 ...
Sara C. Degerholm, Tuula A. Salo, Matti O. Mauramo   +2 more
wiley   +1 more source

Reduced expression of THRβ in papillary thyroid carcinomas: relationship with BRAF mutation, aggressiveness and miR expression [PDF]

, 2015
Purpose Down-regulation of thyroid hormone receptor beta (THRβ) gene has been described in several human malignancies, including thyroid cancer. In this study, we analyzed THRβ mRNA expression in surgical specimens from a series of human papillary ...
Celano, M, D'Agostino, M, DI GIOIA, Cira Rosaria Tiziana, Dima, Mariavittoria, Durante, Cosimo, Giacomelli, Laura, Maggisano, V, Pecce, Valeria, Rosignolo, Francesca, Sponziello, Marialuisa, Verrienti, Antonella   +10 more
core   +1 more source

Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Pet dogs with naturally occurring cancers provide valuable models for comparative oncology and pathology tumour registries offer a powerful resource for onco‐epidemiological research. Here, we analysed the Small Animal Veterinary Surveillance Network (SAVSNET) pathology‐based tumour registry (PTR), one of the largest veterinary tumour ...
José Rodríguez, Antonio Espinosa de los Monteros, Ángelo Santana, P. J. Noble, Alan D. Radford, Francesco Cian, Annika Herrmann, Jenny S. McKay, Matthew Jones, David R. Killick   +9 more
wiley   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Melanocyte differentiation antigen RAB38/NY-MEL-1 induces frequent antibody responses exclusively in melanoma patients [PDF]

, 2018
Expression pattern and immunogenicity are critical issues that define tumor antigens as diagnostic markers and potential targets for immunotherapy.
Bartnick, Tammo, Chen, Yao-Tseng, Dummer, Reinhold, Filonenko, Valeriy, Gati, Asma, Jaeger, Dirk, Jaeger, Elke, Knuth, Alexander, Moch, Holger, Odermatt, Bernhard, Old, Lloyd, Osanai, Kazuhiro, Urosevic, Mirjana, Walton, Senta, Zippelius, Alfred   +14 more
core  

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang, Chung‐I Li, Rui Xin, Jijun Tang, Yan Guo   +4 more
wiley   +1 more source

Aosta Valley animal cancer registry: A collaborative initiative for monitoring cancer burden in animals

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin, Giulio Barigelletti, Caterina Abate, Giovanna Michela Villa, Emilio Bazzocchi, Lorenzo Domenis, Silvia Vuillermoz, Magda Giulia Santini, Barbara Avuzzi, Alessandro Borgini, Giovanna Tagliabue   +10 more
wiley   +1 more source