Results 81 to 90 of about 19,512 (206)

Malignant craniopharyngiomas: Institutional experience and literature review

Brain Pathology, EarlyView.
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen, Isabella W. Zhang, Weiwei Zhang, Jordan M. Burr, Matthew L. Carda, James L. Wisecarver, Nicole Shonka, Jesse L. Cox, Sahara J. Cathcart, Allison Cushman‐Vokoun, Jie Chen   +10 more
wiley   +1 more source

Imaging of adult ocular and orbital pathology - a pictorial review [PDF]

, 2014
Orbital pathology often presents a diagnostic challenge to the reporting radiologist. The aetiology is protean, and clinical input is therefore often necessary to narrow the differential diagnosis.
Brennan, Paul, Galvin, Patrick Leo, Grech, Reuben, Grech, Stephan, Looby, Seamus, Mizzi, Adrian, O'Hare, Alan, Spiteri Cornish, Kurt, Thornton, John   +8 more
core   +1 more source

Presenting Clinical Features of Vitreoretinal Lymphoma

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Vitreoretinal lymphoma is a rare cancer, widely recognised to present diagnostic challenges. We aimed to report information that would support the clinician in considering this diagnosis. Methods We interrogated the International Vitreoretinal B‐Cell Lymphoma Registry for clinical data from patients newly diagnosed with ...
The International Vitreoretinal B‐Cell Lymphoma Registry Investigator Group, Mara Albert‐Fort, Sofia Androudi, Neni Anggraini, Atitaya Apivatthakakul, J. Fernando Arevalo, Meghan K. Berkenstock, Ester Carreño, Anita S.Y. Chan, Soon‐Phaik Chee, Fred K. Chen, Janejit Choovuthayakorn, Luca Cimino, Elisa E. Cornish, Gábor G. Deák, Alexandra L. Farrall, Christina J. Flaxel, Marion Funk, Zsuzsanna Gehl, Pietro Gentile, Debra A. Goldstein, John A. Gonzales, Fabrizio Gozzi, Antonio Hernández‐Pons, Samar Issa, Timothy M. Janetos, Hyeong Min Kim, Min Kim, Jared E. Knickelbein, Zachary A. Kroeger, Paradee Kunavisarut, Rina La Distia Nora, Seung Min Lee, Lyndell L. Lim, Ming Lee Lin, Victor Llorenç, Yunhua Loo, Lucía Martínez‐Costa, Janet M. Matthews, Peter J. McCluskey, David L. McKay, Matteo Menean, Elisabetta Miserocchi, Manabu Mochizuki, Rachael L. Niederer, Roderick F. O’day, Amy S. Pai, Alan G. Palestine, Kessara Pathanapitoon, Mark H.B. Radford, Josephine Richards, Sukhum Silpa‐archa, Joanne L. Sims, Justine R. Smith, Robert T. Swan, Yukiko Terada, Daniel V. Vasconcelos‐Santos, Anagha Vaze, Samanthila Waduthantri, Travers R.E. Weaver, Keryn L. Williams, Se Joon Woo, Richard J. Woodman, Frances Wu, Christine Younan   +64 more
wiley   +1 more source

The prognostic value of Foxp3+ tumor-infiltrating lymphocytes in patients with glioblastoma [PDF]

, 2013
Forkhead box protein 3 (Foxp3) is known as a specific marker for regulatory T cells which contribute to immunosuppression in tumor microenvironment. However, existing studies regarding clinical significance of Foxp3+ tumor-infiltrating lymphocytes (TILs)
Hong-xing Ye, Qi Yue, Xin Zhang, Yin Wang, Ying Mao, Yu Yao, Zun-guo Du   +6 more
core   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Ocular melanoma-when you have seen one, you have not seen them all: a clinical outcome study from the Surveillance, Epidemiology and End Results (SEER) database (1973–2012)

Clinical Ophthalmology, 2017
Krishnaraj Mahendraraj,1 Sneha Shrestha,1 Christine SM Lau,1,2 Ronald S Chamberlain1–4 1Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA; 2Saint George’s University School of Medicine, Grenada, West Indies ...
Mahendraraj K, Shrestha S, Lau CSM, Chamberlain RS   +3 more
doaj  

Telomerase promoter mutations in cancer: an emerging molecular biomarker? [PDF]

, 2014
João Vinagre, Vasco Pinto and Ricardo Celestino contributed equally to the manuscript.Cell immortalization has been considered for a long time as a classic hallmark of cancer cells.
A Glaessl, A Marrone, A Morii, A Okumura, A Preto, A Tallet, AJ Cesare, AM Nistelrooij van, B Heidenreich, C Cifuentes-Rojas, C Gunes, C Harle-Bachor, C Koelsche, C Koelsche, C Miracco, CD Hurst, CH Yang, CK Garcia, CM Buseman, CM Heaphy, CM Heaphy, CN Parris, CW Brennan, CW Greider, D Lotsch, DA Skvortsov, DM Baird, E Gonzalez-Suarez, E Kulla, E Pascolo, EH Blackburn, EM Buckingham, F Egberts, FW Huang, G Aubert, G Liang, GA Scott, GJ Prud’homme, GM Anic, GM Baerlocher, H Arita, H El-Daly, H Nan, H Populo, Helena Pópulo, HY Du, I Kinde, I Landa, J Han, J Jendrzejewski, J Nandakumar, J Vinagre, JC Lindsey, JC Nault, JD Henson, Jorge Lima, José Manuel Lopes, João Vinagre, JP Liu, JP Murnane, JS Reis-Filho, JW Shay, JW Szostak, JY Liau, K Damm, K Perrem, KA Carroll, KG Griewank, KG Griewank, KG Griewank, L Carvalho, L Hayflick, L Montanaro, LA Langford, LS Burke, M Capezzone, M Capezzone, M Dono, M Folini, M Kimura, M Melo, M Remke, M Ruden, M Ueda, Manuel Sobrinho-Simões, Marta Reis, Miguel Melo, MM Gramatges, N Nonoguchi, NW Kim, P Castelo-Branco, P Rudolph, P Scheinberg, P Soares, Paula Boaventura, Paula Soares, PJ Killela, PS Rachakonda, RC Wu, RD Ramirez, RH Vonderheide, Ricardo Celestino, RM Cawthon, RS Taylor, S Bagheri, S Cantara, S Goutagny, S Hiraga, S Horn, S Hreidarsson, S Hu, S Kyo, S Mocellin, S Saleh, S Shete, S Wu, SA Savage, SA Savage, T Liu, T Liu, T Sano, Telmo Catarino, TJ Gross, U Svenson, V Bataille, Valdemar Máximo, Vasco Pinto, X Liu, X Liu, X Liu, X Zhou, Y Allory, Y Jiao, Y Lin, Y Qu, Y Qu, Y Zhao, Y Zhao, YS Cong   +138 more
core   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Two cases of uveitis masquerade syndrome caused by bilateral intraocular large B-cell lymphoma [PDF]

, 2013
Introduction. Sometimes it is not easy to clinically recognize subtle differences between intraocular lymphoma and noninfectious uveitis. The most common lymphoma subtype involving the eye is B-cell lymphoma. Case report.
Jovanović Svetlana, Jovanović Zorica, Marković Vujica, Paović Jelena, Pešić Snežana, Čeperković-Stanković Vesna   +5 more
core   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source