Results 1 to 10 of about 415 (112)

Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain [PDF]

Brazilian Journal of Microbiology, 2018
Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 base pairs, and comprises 5911 coding sequences.
Franciele Maboni Siqueira, Saulo Pavarini, Fabiana Quoos Mayer   +2 more
exaly   +8 more sources

New insights about vaccine effectiveness: Impact of attenuated PRRS-strain vaccination on heterologous strain transmission [PDF]

Vaccine, 2020
Vaccination is the main tool for controlling infectious diseases in livestock. Yet current vaccines only provide partial protection raising concerns about vaccine effectiveness in the field. Two successive transmission trials were performed involving 52 pigs to evaluate the effectiveness of a Porcine Reproductive and Respiratory Syndrome (PRRS ...
Chase-Topping, Margo, Xie, Jiexiong, Pooley, Christopher, Trus, Ivan, Bonckaert, Caroline, Rediger, Kelly, Bailey, Richard, Brown, Helen, Bitsouni, Vasiliki, Barrio , Maria Belen, Gueguen, Sylvie, Nauwynck, Hans, Wilson, Andrea; id_orcid 0000-0002-2658-6973   +12 more
openaire   +6 more sources

Genome stability of the vaccine strain VAC∆6

Vavilov Journal of Genetics and Breeding, 2022
Due to cessation of mass smallpox vaccination in 1980, the collective immunity of humans against orthopoxvirus infections has virtually been lost. Therefore, the risk of spreading zoonotic human orthopoxvirus infections caused by monkeypox and cowpox viruses has increased in the world.
R. A. Maksyutov, S. N. Yakubitskiy, I. V. Kolosova, T. V. Tregubchak, A. N. Shvalov, E. V. Gavrilova, S. N. Shchelkunov   +6 more
openaire   +3 more sources

Toxigence of anthrax vaccine strains

Ukrainian journal of veterinary sciences, 2020
The article presents the results of the studying of anthrax strains and Bacillus anthracis-like strains on the formation of toxins. We found that anthrax vaccine strains actively produce exotoxins to the culture fluid. The amount of specific protein is different under the same incubation conditions and depends on the individual characteristics of the ...
Hanna Zaviriukha, Uliana Yanenko, Nina Kosianchuk   +2 more
openaire   +3 more sources

Candidate cytomegalovirus strain for human vaccination [PDF]

Infection and Immunity, 1975
A strain of human cytomegalovirus called Towne was isolated in WI-38 human fibrolast cell cultures from the urine of an infected infant. It was then passaged 125 times in WI-38, including three clonings, and a pool was prepared in the same cell substrate for use as a potential live attenuated vaccine.
S A, Plotkin, T, Furukawa, N, Zygraich, C, Huygelen   +3 more
openaire   +2 more sources

The challenges of vaccine strain selection

eLife, 2020
New measures of influenza virus fitness could improve vaccine strain selection through more accurate forecasts of the evolution of the virus.
Amanda C Perofsky, Martha I Nelson
openaire   +3 more sources

Genetic Characterization of Measles Vaccine Strains [PDF]

The Journal of Infectious Diseases, 2011
AbstractThe complete genomic sequences of 9 measles vaccine strains were compared with the sequence of the Edmonston wild-type virus. AIK-C, Moraten, Rubeovax, Schwarz, and Zagreb are vaccine strains of the Edmonston lineage, whereas CAM-70, Changchun-47, Leningrad-4 and Shanghai-191 were derived from 4 different wild-type isolates.
Bettina, Bankamp, Makoto, Takeda, Yan, Zhang, Wenbo, Xu, Paul A, Rota   +4 more
openaire   +2 more sources

Moderately Low Effectiveness of the Influenza Quadrivalent Vaccine: Potential Mismatch between Circulating Strains and Vaccine Strains

Vaccines, 2023
The annual seasonal influenza vaccination is the most effective way of preventing influenza illness and hospitalization. However, the effectiveness of influenza vaccines has always been controversial. Therefore, we investigated the ability of the quadrivalent influenza vaccine to induce effective protection.
Maaweya E. Awadalla, Haitham Alkadi, Modhi Alarjani, Abdullah E. Al-Anazi, Mohanad A. Ibrahim, Thamer Ahmad ALOhali, Mushira Enani, Wael Alturaiki, Bandar Alosaimi   +8 more
openaire   +3 more sources

The dimensionality of vaccination intentions: One strain or multiple strains?

Health Psychology
People likely have different attitudes toward different vaccines (e.g., they may hold a positive attitude toward the measles, mumps, and rubella-vaccine while simultaneously hold a neutral attitude toward the flu shot). To examine the dimensionality of vaccination intentions, we measured vaccination intentions toward 16 different diseases.
Mitchell A. M. Matthijssen, Florian van Leeuwen, Mariëlle Cloin, Ien van de Goor, Peter Achterberg   +4 more
openaire   +2 more sources

Live vaccine strain recommendations for the human influenza vaccine

, 2020
Up to 5 million annual influenza infections cause substantial morbidity and mortality in seasonal epidemics around the globe. Human influenza A viruses undergo constant genetic and antigenic drift allowing recurrent infections in the human population. To ensure continued protection against influenza infections, the viral strains used for the production
Klingen, Thorsten, Reimering, Susanne, McHardy, Alice C.   +2 more
openaire   +1 more source