Results 91 to 100 of about 5,753 (291)

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy   +16 more
wiley   +1 more source

The role of the bursa of Fabricius in the development of resistance in infectious laryngotracheitis [PDF]

open access: yes, 1956
Call number: LD2668 .T4 1956 B36Master of ...
Barney, George Harold.
core  

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Diagnostic performance of RFLP-PCR and sarcosine based indirect ELISA versus immunoassays in Brucella infected and vaccinated small ruminants

open access: yesBulgarian Journal of Veterinary Medicine, 2020
This study was carried out for evaluation of the diagnostic performance of different serological assays; buffered acidified plate antigen test (BAPAT), rose bengal plate test (RBPT), immunochroma-tographic assay (ICA), rivanol test (RivT), indirect ELISA
S. Soliman   +4 more
doaj   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Identification of novel neutralizing determinants for protection against HCV

open access: yesHepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua   +12 more
wiley   +1 more source

“In-house” production of DNA size marker from a vaccinal Bacillus anthracis strain

open access: yesIranian Journal of Microbiology, 2015
Background and Objectives: DNA molecular weight marker is widely used in molecular biology experiments incurring considerable costs on low-budget settings.
Mohammad Sekhavati   +6 more
doaj  

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

open access: yesAdvanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang   +9 more
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

open access: yesHepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen   +4 more
wiley   +1 more source

PREPARATION OF MONOSPECIFIC BRUCELLA ANTI-ABORTUS SERUM BASED ON THERMOEXTRACT FROM S-FORM BRUCELLA

open access: yesПроблемы особо опасных инфекций, 2017
Objective of the study is to prepare rabbit monospecific anti-abortus serum to a Brucella S-form thermoextract, as well as to evaluate its activity and specificity. Materials and methods.
L. M. Мikhailov   +7 more
doaj   +1 more source

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