Results 91 to 100 of about 759,009 (305)

Risk factors associated with the intensity of COVID-19 outbreaks in Canadian community settings: a retrospective analysis of outbreak-level surveillance data

BMC Public Health
Background The severity of COVID-19 outbreaks is disproportionate across settings (e.g., long-term care facilities (LTCF), schools) across Canada. Few studies have examined factors associated with outbreak severity to inform prevention and response.
Demy Dam, Michelle Chen, Erin E. Rees, Bethany Cheng, Lynn Sukkarieh, Erin McGill, Yasmina Tehami, Anna Bellos, Jonathan Edwin, Kaitlin Patterson   +9 more
doaj   +1 more source

Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries. [PDF]

, 2012
BACKGROUND: Most health economic evaluations of childhood vaccination only capture the health and short-term economic benefits. Measuring broader, long-term effects of vaccination on productivity and externalities could provide a more complete picture of
Evers, Silvia; id_orcid, van der Putten, Inge, Jit, Mark, van der Putten Inge, Jit Mark, Deogaonkar, Rohan, Evers Silvia, Hutubessy, Raymond, van der Putten, Inge; id_orcid, Silvia Evers, Mark Jit, Hutubessy, Raymond C. W., Deogaonkar Rohan, Evers, Silvia, Hutubessy Raymond, Raymond Hutubessy, Inge van der Putten, Rohan Deogaonkar   +17 more
core   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Adult influenza vaccination coverage before, during and after the COVID-19 pandemic in Canada

BMC Public Health
Background Vaccination prevents seasonal influenza and its complications, particularly among high-risk populations. The COVID-19 pandemic has been reported to impact healthcare behaviors and vaccination patterns.
Ruoke Chen, Nicolas L. Gilbert, Ève Dubé   +2 more
doaj   +1 more source

Determinants of influenza non-vaccination among Canadian children: insights from a nationwide survey

Frontiers in Public Health
BackgroundTo identify determinants influencing Canadian parents’ decision not to vaccinate their children aged 6 months to 17 years against seasonal influenza.MethodsData from the 2022 Childhood COVID-19 Immunization Coverage Survey, a national survey of
Abdallah Alami, Sailly Dave, Caren Uhlik, Marwa Ebrahim, Daniel Krewski, Julie Laroche   +5 more
doaj   +1 more source

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

eLife, 2016
The RIG-I-like receptors (RLRs) play a major role in sensing RNA virus infection to initiate and modulate antiviral immunity. They interact with particular viral RNAs, most of them being still unknown.
Raul Y Sanchez David, Chantal Combredet, Odile Sismeiro, Marie-Agnès Dillies, Bernd Jagla, Jean-Yves Coppée, Marie Mura, Mathilde Guerbois Galla, Philippe Despres, Frédéric Tangy, Anastassia V Komarova   +10 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Factors associated with COVID-19 non-vaccination among children and adolescents with chronic health conditions in Canada: A national cross-sectional study

Vaccine: X
Background: COVID-19 vaccine rollout has prioritized high risk populations, including children with chronic health conditions (CHC), who are at greater risk of severe illness and hospitalization if infected.
Arlanna Pugh, Sailly Dave, Marwa Ebrahim, Julie A. Laroche   +3 more
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

The PPD-specific T-cell clonal response in UK and Malawian subjects following BCG vaccination: a new repertoire evolves over 12 months.

, 2006
Mycobacterium bovis bacille Calmette Guerin vaccination protects against pulmonary tuberculosis in the United Kingdom but not in Malawi. We investigated whether a difference in the clonal T-cell response to BCG vaccination might account for this.
Msiska, GK, Bennett, Andrea A., Fine, Paul E.M., de Lara, CM, Weir, Rosemary E., Ben-Smith, A, Msiska, Glyn K., Bennett, AR, Crampin, Amelia C, Beverley, Peter C.L., Fine, PE, Gorak-Stolinska, Patricia, Weir, RE, Bennett, Andrea R, Fine, Paul EM, Crampin, Amelia C., Ben-Smith, Anne, Lalor, MK, Dockrell, Hazel M., Floyd, Sian, Msiska, Glyn K, Beverley, Peter, de Lara, Catherine M, Beverley, Peter CL, Lalor, Maeve K., Makamo, K, Weir, Rosemary E, Crampin, AC, Gorak-Stolinska, P, Dockrell, HM, Beverley, PC, Lalor, Maeve K, Dockrell, Hazel M, de Lara, Catherine M., Makamo, Kandakuone, Floyd, S   +35 more
core   +1 more source