Results 111 to 120 of about 3,030,606 (198)

The molecular determinants and consequences of recombination in the evolution of human enteroviruses [PDF]

Recombination is an important biological process in a diverse range of viruses, particularly those with single-stranded ribonucleic acid (RNA) genomes including the enteroviruses.
Lowry, Kym
core  

Monitoring the VDPV2 outbreak in Egypt during 2020–2021 highlights the crucial role of environmental surveillance and boosting immunization in combating Poliovirus

BMC Infectious Diseases
Background Poliovirus is a highly infectious enterovirus (EV) that primarily affects children and can lead to lifelong paralysis or even death. Vaccine-derived polioviruses (VDPVs) are a great threat since they are derived from the attenuated virus in ...
Menna R. Shabana, Amira Y. Zaghloul, Tamer H. El Shaarawy, Nooran S. Elleboudy, Khaled M. Aboshanab   +4 more
doaj   +1 more source

A Panel of VHH Antibodies Against Sabin Type 1 Poliovirus D-Antigen Reveals Strain-Specific and Cross-Serotype Reactivity

Viruses
Vaccination remains the primary strategy for poliomyelitis prevention. The D-antigen of poliovirus is a critical component of inactivated polio vaccines, as it induces the production of neutralizing antibodies and provides protective immunity. Therefore,
Maya Ermakova, Sergey Ivanov, Olga Shmeleva, Nadezhda Borisenko, Anna Zyrina, Stepan Chumakov, Igor Levin, Regina Yakupova, Marina Merkulova, Anna Shishova, Yury Ivin, Anastasia Piniaeva, Alexandra Siniugina, Aydar Ishmukhametov   +13 more
doaj   +1 more source

Environmental Surveillance of Polioviruses in Armenia, Colombia before Trivalent Oral Polio Vaccine Cessation

Viruses, 2019
Although acute flaccid paralysis (AFP) surveillance is the “gold standard” for detecting cases of polio, environmental surveillance can provide supplementary information in the absence of paralytic poliomyelitis cases.
María Mercedes González, Magile C. Fonseca, Carlos Andrés Rodríguez, Alejandra María Giraldo, José Joaquín Vila, Jhon Carlos Castaño, Leonardo Padilla, Luis Sarmiento   +7 more
doaj   +1 more source

Poliovirus shedding after sequential immunization of Sabin-strain inactivated polio vaccines and oral attenuated polio vaccines

npj Vaccines
The identification of poliovirus in stool samples post-Oral Poliovirus Vaccine (OPV) immunization is essential for implementing post-eradication monitoring of poliomyelitis.
Yuting Fu, Rufei Ma, Zhimei Zhao, Zhaojun Mo, Zhifang Ying, Jing Li, Hui Ye, Guoliang Li, Xiaochang Liu, Jiangli Liang, Ling Ping, Jingyan Li, Junhui Tao, Qinghai Yang, Dingkai Wei, Li Yi, Hongbo Chen, Jianfeng Wang, Ruiju Jiang, Lei Yu, Wei Cai, Wei Yang, Lei Yue, Mingxue Xie, Qiongzhou Yin, Jing Pu, Chao Hong, Lukui Cai, Yan Deng, Jiana Wen, Yan Ma, Na Gao, Xiaoyu Wang, Hongwei Liao, Qiuyan Ji, Guang Ji, Wenzhu Hu, Qin Gu, Xiaoyue He, Han Chu, Yixian Fu, Jian Zhou, Yu Wen, Xiaolei Yang, Changgui Li, Li Shi, Ting Zhao, Teng Huang, Jingsi Yang   +48 more
doaj   +1 more source

Excretion and clearance of Sabin-like type 3 poliovirus in a child diagnosed with severe combined immunodeficiency

Human Vaccines & Immunotherapeutics
Children with primary immunodeficiency disorder (PID) are at higher risk of developing vaccine-associated paralytic poliomyelitis (VAPP) or vaccine-derived polioviruses (VDPV) infection when inadvertently expose to poliovirus vaccine, oral (OPV). A pilot
Ning Yao, Yang Liu, Zhi-Yong Zhang, Min Tian, Wu-Juan Xie, Hua Zhao, Hong Yang, Lance E. Rodewald, Ning Wen, Zun-Dong Yin, Fu-Zhen Wang, Qing Wang, Jia-Wei Xu   +12 more
doaj   +1 more source

Evaluation of vaccine derived poliovirus type 2 outbreak response options: A randomized controlled trial, Karachi, Pakistan [PDF]

, 2018
Background: Outbreaks of circulating vaccine derived polioviruses type 2 (cVDPV2) remain a risk to poliovirus eradication in an era without live poliovirus vaccine containing type 2 in routine immunization.
Khan, Asia, Saleem, Ali Faisal, Dr, Zaidi, Anita K. M., Yousafzai, Mohammad Tahir, Oberste, M. Steven, Weldon, William C., Mach, Ondrej, Quadri, Farheen, Zaidi, Syed S., Alam, Muhammad M.   +9 more
core  

Development and Validation of a Quantitative RT-qPCR Panel for the Detection and Monitoring of Polioviruses in Wastewater Samples

Microorganisms
Clusters of acute flaccid paralysis (AFP) caused by oral vaccine-derived poliovirus (VDPV) in 2022 and sporadic outbreaks in New York and Gaza highlight the ongoing risk of polio, alongside the persistent global threat posed by wild-type poliovirus. This
Linnet Immaraj, Judy Y. Qiu, Logan A. Brand, Tiejun Gao, Bonita Lee, Michael Parkins, Casey Hubert, Christine O’Grady, Xiaoli Pang   +8 more
doaj   +1 more source

Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants

, 1999
Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
박민수
core   +1 more source

Polio control after certification: major issues outstanding

Bulletin of the World Health Organization, 2004
Now that the global eradication of wild poliovirus is almost within sight, planning for the post-certification era is becoming a priority issue. It is agreed that a stockpile of appropriate polio vaccines will need to be established, and a surveillance ...
Fine Paul E.M., Oblapenko George, Sutter Roland W.   +2 more
doaj