Results 91 to 100 of about 17,275 (222)

Nicotiana benthamiana as a Source of Cowpea Mosaic Virus‐Derived Particles That Specifically Package Designer RNAs

Plant Biotechnology Journal, Volume 24, Issue 1, Page 159-170, January 2026.
ABSTRACT The coupling of replication and encapsidation in the bipartite plant virus, cowpea mosaic virus (CPMV), has been used to specifically incorporate designer RNA molecules into viral particles via transient expression in Nicotiana benthamiana. This is achieved by placing the desired RNA sequence between the 5′ and 3′ UTRs of CPMV RNA‐2 so that ...
H. Peyret, S. N. Shah, Y. Meshcheriakova, J.‐W. Jung, K. Saunders, G. P. Lomonossoff   +5 more
wiley   +1 more source

Next‐Generation Immune Checkpoints and Tumor Microenvironment Modulation in Cancer Immunotherapy

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Immunotherapy has reshaped the oncology landscape by enabling the immune system to recognize and eliminate malignant cells. Although immune checkpoint inhibitors (ICIs) targeting cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4), programmed cell death‐1 (PD‐1), and programmed death‐ligand 1 (PD‐L1) have achieved durable responses in several cancers,
Jhommara Bautista, Carolina E. Echeverría, Iván Maldonado-Noboa, Joseth Adatty-Molina, Salomé Suárez Urresta, Emily C. Coral-Riofrio, Salomé Araujo-Abad, Nikolaos C. Kyriakidis, Andrés López-Cortés, Poorani Gurumallesh Prabu   +9 more
wiley   +1 more source

Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review

Vaccines
Poliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han, Jinbo Xiao, Shiyao Zhang, Tongyue Su, Yinuo Liu, Yong Zhang   +5 more
doaj   +1 more source

Immunodeficiency-associated Vaccine-Derived Poliovirus Type 3 in Infant, South Africa, 2011

Emerging Infectious Diseases, 2012
Patients with primary immunodeficiency are prone to persistently excrete Sabin-like virus after administration of live-attenuated oral polio vaccine and have an increased risk for vaccine-derived paralytic polio.
Nicksy Gumede, Vongani Muthambi, Barry D. Schoub   +2 more
doaj   +1 more source

Systematic Review of Postvaccination Ocular Adverse Events: A Comprehensive Analysis of Published Reports

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Ocular adverse events following COVID‐19 vaccination are well described; however, systematic analyses of non‐COVID antiviral vaccines remain limited. This review aimed to evaluate ocular complications associated with non‐COVID antiviral immunizations, including influenza, varicella‐zoster (VZV), human papillomavirus (HPV), and hepatitis B (HBV)
Yaru Zou, Koju Kamoi, Yuan Zong, Jing Zhang, Mingming Yang, Kyoko Ohno‐Matsui   +5 more
wiley   +1 more source

Are Circulating Type 2 Vaccine-derived Polioviruses (VDPVs) Genetically Distinguishable from Immunodeficiency-associated VDPVs?

Computational and Structural Biotechnology Journal, 2017
Public health response to vaccine-derived poliovirus (VDPV) that is transmitted from person to person (circulating VDPV [cVDPV]) differs significantly from response to virus that replicates in individuals with primary immunodeficiency (immunodeficiency ...
Kun Zhao, Jaume Jorba, Jing Shaw, Jane Iber, Qi Chen, Kelley Bullard, Olen M. Kew, Cara C. Burns   +7 more
doaj   +1 more source

High frequency of Polio-like Enterovirus C strains with differential clustering of CVA-13 and EV-C99 subgenotypes in a cohort of Malawian children [PDF]

, 2018
Enteroviruses (EVs) are among the most commonly detected viruses infecting humans worldwide. Although the prevalence of EVs is widely studied, the status of EV prevalence in sub-Saharan Africa remains largely unknown.
Brouwer, L. (Lieke), Bruning, A.H.L. (Andrea H. L.), Calis, J.C.J. (Job C. J.), Pajkrt, D. (Dasja), Phiri, K.S. (Kamija S.), Rebers, S., Sanden, S.M.G. (Sabine) van der, van Hensbroek, M.B. (Michaël Boele), Wang, S. (Steven), Westerhuis, B.M. (Brenda M.), Wildenbeest, J.G. (Joanne G.), Wolthers, K.C. (Katja)   +11 more
core   +2 more sources

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study.

PLoS ONE, 2018
In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts using the seroprevalence of ...
Maude Pauly, Antony P Black, Phonepaseuth Khampanisong, Phonethipsavanh Nouanthong, Judith M Hübschen, Naphavanh Nanthavong, Kong Sayasinh, Prapan Jutavijittum, Bounthome Samountry, Anonh Xeuatvongsa, Sabine Diedrich, Claude P Muller   +11 more
doaj   +1 more source

Identification of Gastroenteric Viruses by Electron Microscopy Using Higher Order Spectral Features [PDF]

, 2005
Background: Many paediatric illnesses are caused by viral agents, for example, acute gastroenteritis. Electron microscopy can provide images of viral particles and can be used to identify the agents.
Chandran, Vinod, Ong, Chien
core   +2 more sources