Results 71 to 80 of about 3,030,606 (198)

Modeling The Potential Role Of Inactivated Poliovirus Vaccine To Manage The Risks Of Oral Poliovirus Vaccine Cessation

, 2014
Background: The Global Polio Eradication Initiative plans to stop all oral poliovirus vaccine (OPV) after wild poliovirus eradication, starting with serotype 2.
Thompson, Kimberly M., Tebbens, Radboud J.Duintjer   +1 more
core   +1 more source

Vaccine-Derived Polioviruses, Central African Republic, 2019

Emerging Infectious Diseases, 2021
Since May 2019, the Central African Republic has experienced a poliomyelitis outbreak caused by type 2 vaccine-derived polioviruses (VDPV-2s). The outbreak affected Bangui, the capital city, and 10 districts across the country. The outbreak resulted from
Marie-Line Joffret, Joël Wilfried Doté, Nicksy Gumede, Marco Vignuzzi, Maël Bessaud, Ionela Gouandjika-Vasilache   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Vigilancia ambiental de la circulación de poliovirus en tres municipios considerados como punto transitorio de migrantes en Colombia 2017-2019

Infectio, 2021
Objective: To determine the circulation of poliovirus in three municipalities considered as transitory points for migrants in Colombia.Material and Method: Wastewater samples (n = 36) were collected from border municipalities, selected for greater ...
María Mercedes González-De Schroeder
doaj   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, Volume 4, Issue 3, Page 293-301, August 2026.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

A Large Vaccine‐Derived Poliovirus Outbreak on Madura Island—Indonesia, 2005 [PDF]

The Journal of Infectious Diseases, 2008
Between June and October 2005, 45 laboratory-confirmed type 1 vaccine-derived poliovirus (VDPV) cases were identified on Madura Island in Indonesia. Genetic sequencing data on VDPV isolates were consistent with replication and circulation for up to approximately 2 years.
Concepción F, Estívariz, Margaret A, Watkins, Darmawali, Handoko, Rusipah, Rusipah, Jagadish, Deshpande, Bardan J, Rana, Eveline, Irawan, Dyah, Widhiastuti, Mark A, Pallansch, Arun, Thapa, Sholah, Imari   +10 more
openaire   +2 more sources

Updates on intratumoral therapies in melanoma

Cancer, Volume 132, Issue 13, 1 July 2026.
Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma, Alyssa K. Steimle, Janmesh D. Patel, Caroline Burkey, Justin C. Moser, Asad Javed, Hibba tul Rehman, Mustafa Ege Seker, Alexander Birbrair, Orhan S. Ozkan, Mark R. Albertini, Yana G. Najjar, Rajan P. Kulkarni   +12 more
wiley   +1 more source

Prolonged Replication of a Type 1 Vaccine-Derived Poliovirus in an Immunodeficient Patient [PDF]

Journal of Clinical Microbiology, 1998
ABSTRACT VP1 sequences were determined for poliovirus type 1 isolates obtained over a 189-day period from a poliomyelitis patient with common variable immunodeficiency syndrome (a defect in antibody formation). The isolate from the first sample, taken 11 days after onset of paralysis, contained two poliovirus populations, differing from the ...
O M, Kew, R W, Sutter, B K, Nottay, M J, McDonough, D R, Prevots, L, Quick, M A, Pallansch   +6 more
openaire   +2 more sources

Modeling the Dynamics of Oral Poliovirus Vaccine Cessation

, 2014
Background: Oral poliovirus vaccine (OPV) results in an ongoing burden of poliomyelitis due to vaccine-associated paralytic poliomyelitis and circulating vaccine-derived polioviruses (cVDPVs).
Thompson, Kimberly M., Tebbens, Radboud J.Duintjer, Kimberly M. Thompson, Radboud J. Duintjer Tebbens   +3 more
core   +1 more source

Factors associated with the circulation of vaccine-derived polioviruses in children under five in Kilwa, Haut-Katanga province, Democratic Republic of Congo, 2022–2023

BMC Infectious Diseases
Introduction Since the World Health Organization declared the African region free of wild poliovirus in August 2020, vaccine-derived polioviruses (VDPV) have remained the only form of poliovirus still circulating on the continent, including in the ...
Jean Blaise Yobo Iyala, Comlan Cyriaque Degbey, Glodi Elumbu, Betty Kalonji Tshinkenke, N’kpingu Nadakou, Germain Kapour Kieng, Bloc NOMRE TUNI, Jean Paul Makala   +7 more
doaj   +1 more source