Results 71 to 80 of about 17,275 (222)

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission.

PLoS Computational Biology, 2021
Since the global withdrawal of Sabin 2 oral poliovirus vaccine (OPV) from routine immunization, the Global Polio Eradication Initiative (GPEI) has reported multiple circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks.
Michael Famulare, Wesley Wong, Rashidul Haque, James A Platts-Mills, Parimalendu Saha, Asma B Aziz, Tahmina Ahmed, Md Ohedul Islam, Md Jashim Uddin, Ananda S Bandyopadhyay, Mohammed Yunus, Khalequ Zaman, Mami Taniuchi   +12 more
doaj   +1 more source

Assessment of poliovirus antibody seroprevalence in high risk areas for vaccine derived poliovirus transmission in Madagascar [PDF]

Heliyon, 2018
Vaccine-derived polioviruses (VDPV) outbreaks typically occur in areas of low poliovirus immunity. Madagascar successfully eradicated wild poliovirus in 1997; however, multiple VDPV outbreaks have occurred since then, and numerous vaccination campaigns have been carried out to control the VDPV outbreaks. We conducted a survey of poliovirus neutralizing
Richter Razafindratsimandresy, Ondrej Mach, Jean-Michel Heraud, Barivola Bernardson, William C. Weldon, M. Steven Oberste, Roland W. Sutter   +6 more
openaire   +3 more sources

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Factors associated with the circulation of vaccine-derived polioviruses in children under five in Kilwa, Haut-Katanga province, Democratic Republic of Congo, 2022–2023

BMC Infectious Diseases
Introduction Since the World Health Organization declared the African region free of wild poliovirus in August 2020, vaccine-derived polioviruses (VDPV) have remained the only form of poliovirus still circulating on the continent, including in the ...
Jean Blaise Yobo Iyala, Comlan Cyriaque Degbey, Glodi Elumbu, Betty Kalonji Tshinkenke, N’kpingu Nadakou, Germain Kapour Kieng, Bloc NOMRE TUNI, Jean Paul Makala   +7 more
doaj   +1 more source

Excretion of Wild-Type and Vaccine-Derived Poliovirus in the Feces of Poliovirus Receptor-Transgenic Mice [PDF]

Journal of Virology, 2003
ABSTRACT The emergence of circulating vaccine-derived poliovirus (cVDPV) strains in suboptimally vaccinated populations is a serious threat to the global poliovirus eradication. The genetic determinants for the transmissibility phenotype of polioviruses, and in particularly of cVDPV strains, are currently unknown.
Hein J, Boot, Daniella T J, Kasteel, Anne-Marie, Buisman, Tjeerd G, Kimman   +3 more
openaire   +2 more sources

Sociodemographic and Clinical Factors Impact Non‐Live Vaccine Coverage After Pediatric Solid Organ Transplantation: A Single Center Study

Pediatric Transplantation, Volume 30, Issue 3, March 2026.
This single‐center retrospective study of pediatric solid organ transplant recipients found that vaccine‐specific serologies were rarely utilized to guide post‐transplant vaccination practices. Additionally, older age at the time of transplant, private insurance, and heart transplantation were identified as risk factors for delayed and incomplete non ...
Adam Z. Blatt, Yunfei Wang, Yeh‐Chung Chang, Sarah M. Heston   +3 more
wiley   +1 more source

Circulating vaccine-derived polioviruses: current state of knowledge

Bulletin of the World Health Organization, 2004
Within the past 4 years, poliomyelitis outbreaks associated with circulating vaccine-derived polioviruses (cVDPVs) have occurred in Hispaniola (2000-01), the Philippines (2001), and Madagascar (2001-02).
Kew Olen M., Wright Peter F., Agol Vadim I., Delpeyroux Francis, Shimizu Hiroyuki, Nathanson Neal, Pallansch Mark A.   +6 more
doaj  

Polio eradication: A complex end game [PDF]

, 2012
published_or_final_versio
Abraham, T
core   +1 more source