Results 51 to 60 of about 3,030,606 (198)
Lessons from Vaccine-Related Poliovirus in Israel, UK and USA
Genetic variants of vaccine poliovirus type 2, imported from an unknown source, were detected in waste waters in Jerusalem, London and New York in early 2022.
T. Jacob John +3 more
core +1 more source
Background Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal–oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein.
Joanne Hassan +6 more
doaj +1 more source
Vaccine-Derived Poliovirus: Epidemiology, Types, Global Response and Future Prospectives
The genetic biodiversity of Polio virus transmission is a key indicator for epidemiologists to examine the transmission patterns of individual virus lines or families.
Menna R. Shabana +3 more
doaj +1 more source
The growing threat of wild poliovirus 1 and vaccine-derived cases in the COVID-19 era
The detection of people with paralytic cases of wild poliovirus 1 (WPV1) in two African countries (ie, Malawi in February, 2022, and Mozambique in May, 2022) outside endemic areas of WPV1 transmission (ie, Pakistan and Afghanistan) will become a serious ...
Carlos Franco-Paredes +14 more
core +1 more source
In 2014, inactivated poliovirus vaccine (IPV) campaigns were implemented in Nigeria and Pakistan after clinical trials showed that IPV boosts intestinal immunity in children previously given oral poliovirus vaccine (OPV). We estimated the effect of these
George Shirreff +4 more
doaj +1 more source
Stem Cell Transplant in Immune-deficiency-associated Vaccine-derived Poliovirus. [PDF]
Abstract Patients with severe primary immunodeficiency are at risk for complications from live-attenuated vaccines. Here, we report a case of a vaccine-associated paralytic polio and Bacille Calmette-Guérin disease in a 6-month-old girl with severe combined immunodeficiency resulting from homozygous recombinant activating gene 1 ...
Ranchod H +17 more
europepmc +4 more sources
Preventing Vaccine-Derived Poliovirus Emergence during the Polio Endgame
Reversion and spread of vaccine-derived poliovirus (VDPV) to cause outbreaks of poliomyelitis is a rare outcome resulting from immunisation with the live-attenuated oral poliovirus vaccines (OPVs). Global withdrawal of all three OPV serotypes is therefore a key objective of the polio endgame strategic plan, starting with serotype 2 (OPV2) in April 2016.
Margarita Pons-Salort +7 more
openaire +5 more sources
Enterovirus infections in children
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen +11 more
wiley +1 more source
Long-Term Circulation of Vaccine-Derived Poliovirus That Causes Paralytic Disease [PDF]
ABSTRACT Successful implementation of the global poliomyelitis eradication program raises the problem of vaccination against poliomyelitis in the posteradication era. One of the options under consideration envisions completely stopping worldwide the use of the Sabin vaccine.
Elena A, Cherkasova +6 more
openaire +2 more sources
Polio eradication in Ghana: past, present, and future
IntroductionGhana joined the Global Polio Eradication Initiative in 1996 to interrupt wild poliovirus transmission in the country. This was a collaborative effort by the Ghana Health Service (Disease Surveillance Department and the Expanded Program on ...
John Kofi Odoom +19 more
doaj +1 more source

