Results 51 to 60 of about 17,275 (222)

Epidemics to eradication: the modern history of poliomyelitis [PDF]

, 2007
Poliomyelitis has afflicted humankind since antiquity, and for nearly a century now, we have known the causative agent, poliovirus. This pathogen is an enterovirus that in recent history has been the source of a great deal of human suffering.
Nidia H De Jesus
core   +2 more sources

Has wild poliovirus been eliminated from Nigeria?

, 2015
Wild poliovirus type 3 (WPV3) has not been seen anywhere since the last case of WPV3-associated paralysis in Nigeria in November 2012. At the time of writing, the most recent case of wild poliovirus type 1 (WPV1) in Nigeria occurred in July 2014, and ...
Famulare, Michael
core   +3 more sources

Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. [PDF]

, 2018
Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection.
Hu, Q, Ke, X, Li, P, Liu, Y, Luo, D, Miao, Y, Sun, J, Tan, Z, Wang, H, Wang, T, Xu, F, Zhang, Y, Zheng, Z   +12 more
core   +1 more source

Polio eradication in Ghana: past, present, and future

Frontiers in Tropical Diseases
IntroductionGhana joined the Global Polio Eradication Initiative in 1996 to interrupt wild poliovirus transmission in the country. This was a collaborative effort by the Ghana Health Service (Disease Surveillance Department and the Expanded Program on ...
John Kofi Odoom, Dennis Odai Laryea, Nana Afia Asante Ntim, Keren Attiku, Michael Adjabeng, Ewurabena Oduma Duker, Comfort Nuamah Antwi, Emmanuel Gberbi, Isaac Baffoe-Nyarko, Patience Lartekai Adams, Angelina Evelyn Dickson, Jessica Dufie Boakye, Jude Yayra Mensah, Christabel Odoom, Sharon Ansong Bimpong, Deborah Odame, Gayheart Deladem Agboste, Nancy Odoom, Franklin Asiedu-Bekoe, Evangeline Obodai   +19 more
doaj   +1 more source

Population Immunity against Serotype-2 Poliomyelitis Leading up to the Global Withdrawal of the Oral Poliovirus Vaccine: Spatio-temporal Modelling of Surveillance Data. [PDF]

, 2016
BACKGROUND: Global withdrawal of serotype-2 oral poliovirus vaccine (OPV2) took place in April 2016. This marked a milestone in global polio eradication and was a public health intervention of unprecedented scale, affecting 155 countries.
Blake, Isobel M, Etsano, Andrew, Grassly, Nicholas C, Jafari, Hamid, Molodecky, Natalie A, O'Reilly, Kathleen M, Pons-Salort, Margarita, Safdar, Rana M, Vaz, Rui Gama, Wadood, Mufti Zubair   +9 more
core   +4 more sources

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

A RT-PCR method for selective amplification and phenotypic characterization of all three serotypes of Sabin-related polioviruses from viral mixtures

Memorias do Instituto Oswaldo Cruz, 2012
Outbreaks caused by vaccine-derived polioviruses are challenging the final eradication of paralytic poliomyelitis. Therefore, the surveillance of the acute flaccid paralysis cases based on poliovirus isolation and characterization remains an essential ...
Eliane Veiga da Costa, Renata de Mendonça Campos, Fernando Neto Tavares, Cátia Regina Valério Grégio, Fernanda Marcicano Burlandy, Edson Elias da Silva   +5 more
doaj   +1 more source

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, January 2018–June 2019 [PDF]

MMWR. Morbidity and Mortality Weekly Report, 2019
Certification of global eradication of indigenous wild poliovirus type 2 occurred in 2015 and of type 3 in 2019. Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988 and broad use of live, attenuated oral poliovirus vaccine (OPV), the number of wild poliovirus cases has declined >99.99% (1).
Jorba, Jaume, Diop, Ousmane M., Iber, Jane, Henderson, Elizabeth, Zhao, Kun, Quddus, Arshad, Sutter, Roland, Vertefeuille, John F., Wenger, Jay, Wassilak, Steven G.F., Pallansch, Mark A., Burns, Cara C.   +11 more
openaire   +2 more sources

Serological survey on immunity status against polioviruses in children and adolescents living in a border region, Apulia (Southern Italy) [PDF]

, 2008
BACKGROUND: In 1988 the World Health Assembly adopted the goal to eradicate poliomyelitis by routine immunization using Oral Polio Vaccine (OPV). On 21 June 2002 the WHO European Region was declared polio-free.
Silvio Tafuri, Rosa Prato, Domenico Martinelli, Agata Calvario, Anna Bozzi, Michele Labianca, Annamaria Patti, Pietro Luigi Lopalco, Cinzia Germinario, World Health Assembly GSWHO, ME Birmingham, CA De Quardos, G Oblapenko, SG Wassilak, G Oblapenko, JM Borgono, WHO, Geneva, D Greco, WHO, K Esteves, SA Plotkin, O Kew, H Shimizu, D Rousset, CF Yang, Center for Disease Control and Prevention, J Gaudelus, I Mastroeni, A Pianetti, PL Lopalco, R Prato, WHO, AM Patti, G Stagni, A Volpi, S Majori, PE Fine   +36 more
core   +2 more sources

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

Acta Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz, Raz Somech, Dan Dominissini, Nathan Keller, Efrat Dresner, Michal Paret, Gilad Sherman, Guy Katzenellenbogen, Elina Gelman, Keren Asraf, Ram Doolman, Atar Lev, Amos J. Simon, Helly Vernitsky, Assaf Barg, Hana Golan, Amos Toren, Michal Stein   +17 more
wiley   +1 more source