Results 41 to 50 of about 3,030,606 (198)

Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates [PDF]

, 2014
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of ...
David J Evans, Woodman, Andrew, Andrew Woodman, Kym Lowry (222718), Jonathan Cook (3435386), Andrew Woodman (577477), Cook, Jonathan, Cook, Jonathan P., David J. Evans (208308), Lowry, Kym, David J. Evans, Evans, David J., Kym Lowry, Jonathan Cook   +13 more
core   +1 more source

Measures counteracting 2016 spread of vaccine-derived poliomyelitis virus type 2 in Russian Federation

Инфекция и иммунитет, 2020
Since April 2016 after global cessation of using trivalent oral poliovirus vaccine (tOPV) and switch to bivalent OPV consisting of polioviruses types 1 and 3 (the “switch”), any isolation of type 2 poliovirus has been regarded as an event of extreme ...
A. Yu. Popova, E. B. Ezhlova, A. A. Melnikova, N. S. Morozova, Yu. M. Mikhailova, O. E. Ivanova, L. I. Kozlovskaya, T. P. Eremeeva, A. P. Gmyl, E. A. Korotkova, O. Yu. Baykova, A. Yu. Krasota, А. V. Ivanenko, M. S. Yarmolskaya, I. V. Kovalchuk, E. N. Romanenko   +15 more
doaj   +1 more source

Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine

Human Vaccines & Immunotherapeutics, 2021
The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao, Jing Li, Hongyuan Shi, Hui Ye, Rufei Ma, Yuting Fu, Xiaochang Liu, Guoliang Li, Xiaolei Yang, Zhimei Zhao, Jingsi Yang   +10 more
doaj   +1 more source

Transmission of Imported Vaccine‐Derived Poliovirus in an Undervaccinated Community in Minnesota [PDF]

The Journal of Infectious Diseases, 2009
Oral poliovirus vaccine (OPV) has not been used in the United States since 2000. Type 1 vaccine-derived poliovirus (VDPV) was identified in September 2005, from an unvaccinated Amish infant hospitalized in Minnesota with severe combined immunodeficiency.
James P, Alexander, Kristen, Ehresmann, Jane, Seward, Gary, Wax, Kathleen, Harriman, Susan, Fuller, Elizabeth A, Cebelinski, Qi, Chen, Jaume, Jorba, Olen M, Kew, Mark A, Pallansch, M Steven, Oberste, Mark, Schleiss, Jeffrey P, Davis, Bryna, Warshawsky, Susan, Squires, Harry F, Hull   +16 more
openaire   +2 more sources

Long-Term Excretion of Vaccine-Derived Poliovirus by a Healthy Child [PDF]

Journal of Virology, 2004
ABSTRACT A child was found to be excreting type 1 vaccine-derived poliovirus (VDPV) with a 1.1% sequence drift from Sabin type 1 vaccine strain in the VP1 coding region 6 months after he was immunized with oral live polio vaccine. Seventeen type 1 poliovirus isolates were recovered from stools taken from this child during the following 4 ...
Javier, Martín, Kofi, Odoom, Gráinne, Tuite, Glynis, Dunn, Nicola, Hopewell, Gill, Cooper, Catherine, Fitzharris, Karina, Butler, William W, Hall, Philip D, Minor   +9 more
openaire   +2 more sources

Circulation of Type 2 Vaccine-Derived Poliovirus in China in 2018-2019. [PDF]

Open Forum Infect Dis, 2021
Abstract Background China implemented the globally synchronized switch from trivalent oral poliovirus vaccine (tOPV) to bivalent OPV (bOPV) on May 1, 2016. During April 2018 to May 2019, the first outbreak caused by type 2 circulating vaccine-derived poliovirus (cVDPV2) after the switch occurred in ...
Zhao H, Ma X, Tang H, Zhang Y, Chen N, Kaisaier W, Wang Q, Wang C, Zhu S, Qi Q, Liu Y, Ma Q, Yang Q, Li J, Wang D, Li X, Xiao J, Zhu H, Xu W, Tong W, Yan D.   +20 more
europepmc   +3 more sources

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

Frontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin, Yi Liao, Yi Liao, Marina Takane, Kathleen Dooling, Stuart Gilmour, Ondrej Mach, Olen M. Kew, Olen M. Kew, Roland W. Sutter, The iVDPV Working Group, Ousmane Diop, Nicksy Gumede Moeletsi, Raffaella Williams, Mohamed Seghier, Francis Delpeyroux, Gloria Rey Benito, Maria Cecilia Freire, Cara Burns, Humayun Asghar, Salman Sharif, Jagadish Deshpande, Shohreh Shahmahmoodi, Henda Triki, Laila E Bassioni, Amina Al-Jardani, Eugene Merav Weil Gavrilin, Javier Martín, Sirima Pattamadilok, Sunethra Gunasena, Yan Zhang, Wenbo Xu   +31 more
doaj   +1 more source

Population and Geospatial Risks of Vaccine-Derived Poliovirus Type-2 in the Democratic Republic of the Congo [PDF]

, 2021
Poliovirus, once a global pandemic is now in its endgame eradication stages. Currently, wild poliovirus type 2 and 3 have been declared eradicated by the World Health Organization (WHO) and wild type 1 is circulating in just two remaining countries.
Halbrook, Megan
core   +1 more source

Managing the risk of circulating vaccine-derived poliovirus during the endgame: oral poliovirus vaccine needs [PDF]

BMC Infectious Diseases, 2015
The Global Polio Eradication Initiative plans for coordinated cessation of oral poliovirus vaccine (OPV) use, beginning with serotype 2-containing OPV (i.e., OPV2 cessation) followed by the remaining two OPV serotypes (i.e., OPV13 cessation). The risk of circulating vaccine-derived poliovirus (cVDPV) outbreaks after OPV cessation of any serotype ...
Duintjer Tebbens, Radboud J., Thompson, Kimberly M.   +1 more
openaire   +2 more sources

The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda

Virology Journal, 2018
Background The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). Methods In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases ...
Mary Bridget Nanteza, Barnabas Bakamutumaho, Annet Kisakye, Prossy Namuwulya, Henry Bukenya, Edson Katushabe, Josephine Bwogi, Charles Rutebarika Byabamazima, Raffaella Williams, Nicksy Gumede   +9 more
doaj   +1 more source