Results 61 to 70 of about 3,030,606 (198)

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

Acta Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz, Raz Somech, Dan Dominissini, Nathan Keller, Efrat Dresner, Michal Paret, Gilad Sherman, Guy Katzenellenbogen, Elina Gelman, Keren Asraf, Ram Doolman, Atar Lev, Amos J. Simon, Helly Vernitsky, Assaf Barg, Hana Golan, Amos Toren, Michal Stein   +17 more
wiley   +1 more source

Modelling the spread of serotype-2 vaccine derived-poliovirus outbreak in Pakistan and Afghanistan to inform outbreak control strategies in the context of the COVID-19 pandemic [PDF]

, 2021
Background Since July 2019, Pakistan and Afghanistan have been facing an outbreak of serotype-2 circulating vaccine derived poliovirus (cVDPV2) in addition to continued transmission of serotype-1 wild poliovirus (WPV1) and SARS-CoV-2 in 2020 ...
Shukla, Hemant, Quddus, Arshad, Molodecky, Natalia A, Zaffran, Michel, Blake, Isobel M, Sutter, Roland W, Mahamud, Abdirahman, Bandyopadhyay, Ananda S, Jafari, Hamid, Safdar, Rana M, Ahmed, Jamal A, Grassly, Nicholas C   +11 more
core   +1 more source

A RT-PCR method for selective amplification and phenotypic characterization of all three serotypes of Sabin-related polioviruses from viral mixtures

Memorias do Instituto Oswaldo Cruz, 2012
Outbreaks caused by vaccine-derived polioviruses are challenging the final eradication of paralytic poliomyelitis. Therefore, the surveillance of the acute flaccid paralysis cases based on poliovirus isolation and characterization remains an essential ...
Eliane Veiga da Costa, Renata de Mendonça Campos, Fernando Neto Tavares, Cátia Regina Valério Grégio, Fernanda Marcicano Burlandy, Edson Elias da Silva   +5 more
doaj   +1 more source

Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak

, 2017
<p>Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: a retrospective study</p ...
Sabine Diedrich (4870441), Phonethipsavanh Nouanthong, Judith M. Hübschen, Naphavanh Nanthavong (729478), Kong Sayasinh, Prapan Jutavijittum, Judith M. Hübschen (287707), Kong Sayasinh (5220665), Bounthome Samountry, Claude P. Muller, Maude Pauly, Anonh Xeuatvongsa, Prapan Jutavijittum (331435), Anonh Xeuatvongsa (292624), Phonethipsavanh Nouanthong (723304), Claude P. Muller (106167), Phonepaseuth Khampanisong, Maude Pauly (669810), Naphavanh Nanthavong, Antony P. Black, Sabine Diedrich, Bounthome Samountry (331436), Antony P. Black (375774), Phonepaseuth Khampanisong (5220668)   +23 more
core   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

An Outbreak of Poliomyelitis Caused by Type 1 Vaccine‐Derived Poliovirus in China [PDF]

The Journal of Infectious Diseases, 2006
In May-July 2004, type 1 vaccine-derived poliovirus (VDPV) was isolated from 2 case patients with polio and a contact of a third case patient in Guizhou Province.We conducted a field investigation of the outbreak, characterized outbreak isolates, and retrospectively reviewed national polio surveillance data for other VDPVs.Case patients were ...
Xiaofeng, Liang, Yong, Zhang, Wenbo, Xu, Ning, Wen, Shuyan, Zuo, Lisa A, Lee, Jingjin, Yu   +6 more
openaire   +2 more sources

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Environmental Isolation of Circulating Vaccine-Derived Poliovirus After Interruption of Wild Poliovirus Transmission — Nigeria, 2016 [PDF]

MMWR. Morbidity and Mortality Weekly Report, 2016
In September 2015, more than 1 year after reporting its last wild poliovirus (WPV) case in July 2014 (1), Nigeria was removed from the list of countries with endemic poliovirus transmission,* leaving Afghanistan and Pakistan as the only remaining countries with endemic WPV. However, on April 29, 2016, a laboratory-confirmed, circulating vaccine-derived
Andrew, Etsano, Eunice, Damisa, Faisal, Shuaib, Gatei Wa, Nganda, Ogu, Enemaku, Samuel, Usman, Adekunle, Adeniji, Jaume, Jorba, Jane, Iber, Chima, Ohuabunwo, Chimeremma, Nnadi, Eric, Wiesen   +11 more
openaire   +2 more sources

Epidemiology and vaccination strategies against type-2 vaccine -derived poliovirus [PDF]

In 1988, the World Health Assembly passed a resolution to eradicate poliomyelitis, a disease which was endemic in 125 countries and paralyzed 350,000 children per year.
Macklin, GR
core   +1 more source

The evolving role of immunotherapy in ovarian cancer

Cancer, Volume 132, Issue 18, 15 September 2026.
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani, Laura Venegas, Amit M. Oza   +2 more
wiley   +1 more source