Results 81 to 90 of about 3,030,606 (198)
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
Circulating vaccine-derived polioviruses: current state of knowledge
Within the past 4 years, poliomyelitis outbreaks associated with circulating vaccine-derived polioviruses (cVDPVs) have occurred in Hispaniola (2000-01), the Philippines (2001), and Madagascar (2001-02).
Kew Olen M. +6 more
doaj
A Protocol of National Mixed‐Methods Assessment of Childhood and Maternal Immunization
ABSTRACT Background and Aims Accurate measurement of routine immunization coverage is essential for detecting immunity gaps, guiding programmatic responses, and supporting equitable vaccine delivery. Iran's Expanded Programme on Immunization has achieved high coverage, but administrative estimates can mask some disparities.
Seyed Aria Nejadghaderi +8 more
wiley +1 more source
The risk of type 2 oral polio vaccine use in post-cessation outbreak response
Background Wild type 2 poliovirus was last observed in 1999. The Sabin-strain oral polio vaccine type 2 (OPV2) was critical to eradication, but it is known to revert to a neurovirulent phenotype, causing vaccine-associated paralytic poliomyelitis.
Kevin A. McCarthy +4 more
doaj +1 more source
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei +9 more
wiley +1 more source
Selection and characterization of vaccine strain for Enterovirus 71 vaccine development
[[abstract]]Enterovirus 71 (EV71) has recently emerged as an important neurotropic virus in Asia because effective medications and prophylactic vaccine against EV71 infection are not available.
Chang, JY;Chang, CP;Tsai, HH;Lee, CD;Lian, WC;Ih Jen, S;Sai, IH;Liu, CC;Chou, AH;Lu, YJ;Chen, CY;Lee, PH;Chiang, JR;Chong, PC
core +1 more source
Past and Present Vaccinations in Sweden
Acta Paediatrica, EarlyView.
Sven Arne Silfverdal
wiley +1 more source
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA
ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley +1 more source
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source

