Results 31 to 40 of about 3,030,606 (198)

Excretion of Wild-Type and Vaccine-Derived Poliovirus in the Feces of Poliovirus Receptor-Transgenic Mice [PDF]

Journal of Virology, 2003
ABSTRACT The emergence of circulating vaccine-derived poliovirus (cVDPV) strains in suboptimally vaccinated populations is a serious threat to the global poliovirus eradication. The genetic determinants for the transmissibility phenotype of polioviruses, and in particularly of cVDPV strains, are currently unknown.
Hein J, Boot, Daniella T J, Kasteel, Anne-Marie, Buisman, Tjeerd G, Kimman   +3 more
openaire   +4 more sources

Reemergence of Recombinant Vaccine‐Derived Poliovirus Outbreak in Madagascar [PDF]

The Journal of Infectious Diseases, 2008
After the 2001-2002 poliomyelitis outbreak due to recombinant vaccine-derived polioviruses (VDPVs) in the Toliara province of Madagascar, another outbreak reoccurred in the same province in 2005.We conducted epidemiological and virological investigations for each polio case patient and for their contacts.From May to August 2005, a total of 5 cases of ...
Rakoto-Andrianarivelo, Mala, Gumede, Nicksy, Jegouic, Sophie, Balanant, Jean, Andriamamonjy, Seta N., Rabemanantsoa, Sendraharimanana, Birmingham, Maureen, Randriamanalina, Bakolalao, Nkolomoni, Léon, Venter, Marietjie, Schoub, Barry D., Delpeyroux, Francis, Reynes, Jean-Marc   +12 more
openaire   +4 more sources

Environmental Monitoring for Enteroviruses in Maputo, Mozambique—2018

Pathogens, 2022
Due to the possibility of wild poliovirus importation from endemic regions and the high circulation of vaccine-derived poliovirus type 2 in the African region, Mozambique implemented a surveillance program to monitor the circulation of enteroviruses in ...
Diocreciano Matias Bero, Sheila António Nhassengo, Ivanildo Pedro Sousa, Silas Oliveira de Sousa, Raiana Scerni Machado, Amanda Meireles Nunes Dias, Cristiane de Sousa Ferreira, Fernanda Marcicano Burlandy, Nilsa de Deus, Edson Elias da Silva   +9 more
doaj   +1 more source

Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread. [PDF]

Nat Microbiol
Abstract Outbreaks of vaccine-derived poliovirus type 2 (cVDPV2) have become a major threat to polio eradication. However, variations in spatiotemporal spread have not been quantified. Here we analysed cVDPV2 cases and wild poliovirus type 1 sequences to uncover spatiotemporal patterns and drivers of poliovirus ...
Candido DDS, Dellicour S, Cooper LV, Prete CA, Jorgensen D, Uzzell CB, Voorman A, Lyons H, Klapsa D, Majumdar M, Arowolo K, Peak CM, Bandyopadhyay AS, Martin J, Grassly NC, Blake IM.   +15 more
europepmc   +3 more sources

Sabin polio virus protein 1 (VP1) evolution in patients with acute flaccid paralysis from 2010 to 2016 in Uganda

Virology Journal, 2023
Acute flaccid paralysis (AFP) is a rare side effect of the oral polio vaccine but can be associated with outbreaks and permanent disability in patients harboring circulating vaccine-derived polioviruses (cVDPVs).
Mary Bridget Nanteza, Barnabas Bakamutumaho, Phionah Tushabe, Prossy Namuwulya, Molly Birungi, Rajab Dhatemwa, James Peter Eliku, Mayi Tibanagwa, Proscovia Kakooza, Henry Bukenya, Josephine Bwogi, Charles Rutebarika Byabamazima   +11 more
doaj   +1 more source

Protecting investments in polio eradication: the past, present and future of surveillance for acute flaccid paralysis. [PDF]

, 2004
In September 2003 a WHO consultation group on vaccine-derived polioviruses (VDPV) concluded that in order to prevent future generations of paralytic polio after interruption of transmission of wild poliovirus, the use of trivalent oral polio vaccine (OPV)
D. L. HEYMANN, E. M. DE GOURVILLE, Heymann, DL, R. B. AYLWARD, Aylward, RB, De Gourville, EM   +5 more
core   +1 more source

Evolution of Circulating Wild Poliovirus and of Vaccine-Derived Poliovirus in an Immunodeficient Patient: a Unifying Model [PDF]

Journal of Virology, 2000
ABSTRACT We determined nucleotide sequences of the VP1 and 2AB genes and portions of the 2C and 3D genes of two evolving poliovirus lineages: circulating wild viruses of T geotype and Sabin vaccine-derived isolates from an immunodeficient patient.
G V, Gavrilin, E A, Cherkasova, G Y, Lipskaya, O M, Kew, V I, Agol   +4 more
openaire   +2 more sources

Achieving High Poliovirus Antibody Seroprevalence in Areas at Risk of Vaccine-Derived Poliovirus Transmission—Niger Experience [PDF]

Open Forum Infectious Diseases, 2021
Abstract Background Outbreaks of vaccine-derived poliovirus type 2 (VDPV2) continue to expand across Africa. We conducted a serological survey of polio antibodies in high–polio risk areas of Niger to assess risk of poliovirus outbreaks. Methods
Ousmane, Sani, Ibrahim, Dan Dano, Goel, Ajay, Hendley, William S, Mainou, Bernardo A, Palmer, Tess, Diaha, Aissata, Greene, Sharon A, Mach, Ondrej   +8 more
openaire   +2 more sources

Low rates of repeat HIV testing despite increased availability of antiretroviral therapy in rural Tanzania: findings from 2003-2010. [PDF]

, 2013
BACKGROUND: HIV counselling and testing (HCT) services can play an important role in HIV prevention by encouraging safe sexual behaviours and linking HIV-infected clients to antiretroviral therapy (ART).
Mtenga, Baltazar, Todd Jim, Baltazar Mtenga, Wringe Alison, Marston, Milly, Cawley, Caoimhe, Clark, Benjamin, Caoimhe Cawley, Todd, Jim, Urassa, Mark, Isingo, Raphael, Isingo Raphael, Urassa Mark, Benjamin Clark, Milly Marston, Zaba Basia, Wringe, Alison, Alison Wringe, Clark Benjamin, Mark Urassa, Zaba, Basia, Marston Milly, Raphael Isingo, Cawley Caoimhe, Mtenga Baltazar, Basia Zaba, Jim Todd   +26 more
core   +1 more source

Circulation of Type 1 Vaccine-Derived Poliovirus in the Philippines in 2001 [PDF]

Journal of Virology, 2004
ABSTRACT In 2001, highly evolved type 1 circulating vaccine-derived poliovirus (cVDPV) was isolated from three acute flaccid paralysis patients and one contact from three separate communities in the Philippines. Complete genomic sequencing of these four cVDPV isolates revealed that the capsid region was derived from the Sabin 1 vaccine strain
Hiroyuki, Shimizu, Bruce, Thorley, Fem Julia, Paladin, Kerri Anne, Brussen, Vicki, Stambos, Lilly, Yuen, Andi, Utama, Yoshio, Tano, Minetaro, Arita, Hiromu, Yoshida, Tetsuo, Yoneyama, Agnes, Benegas, Sigrun, Roesel, Mark, Pallansch, Olen, Kew, Tatsuo, Miyamura   +15 more
openaire   +2 more sources