Results 171 to 180 of about 3,030,606 (198)

Circulation of a type 2 vaccine-derived poliovirus, Egypt.

Releve epidemiologique hebdomadaire, 2001
openaire   +1 more source

Immunodeficiency-related vaccine-derived poliovirus (iVDPV) cases: A systematic review and implications for polio eradication

Vaccine, 2015
Background: Vaccine-derived polioviruses (VDPVs), strains of poliovirus mutated from the oral polio vaccine, pose a challenge to global polio eradication.
Yvonne Maldonado, Marisa Holubar
exaly   +3 more sources

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Implications of a Circulating Vaccine-Derived Poliovirus in Nigeria

New England Journal of Medicine, 2010
The largest recorded outbreak of a circulating vaccine-derived poliovirus (cVDPV), detected in Nigeria, provides a unique opportunity to analyze the pathogenicity of the virus, the clinical severity of the disease, and the effectiveness of control measures for cVDPVs as compared with wild-type poliovirus (WPV).We identified cases of acute flaccid ...
Helen E. Jenkins, R. Bruce Aylward, Alex Gasasira, Christl A. Donnelly, Michael Mwanza, Jukka Corander, Sandra Garnier, Claire Chauvin, Emmanuel Abanida, Muhammad Ali Pate, Festus Adu, Marycelin Baba, Nicholas C. Grassly   +12 more
openaire   +4 more sources

Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir

Pediatric Infectious Disease Journal, 2020
Pocapavir exhibits antiviral activity against both polio and nonpolio enteroviruses. There is limited experience of the use of this investigational drug in young children with enteroviral infection. We describe the successful clearance of prolonged immunodeficiency-associated vaccine-derived type 3 poliovirus infection by pocapavir in an infant with ...
Julie, Copelyn, Jeffrey R, Hincks, Jo M, Wilmshurst, Wonita, Petersen, Wayne, Howard, Sabelle, Jallow, Shelina, Moonsamy, Lerato, Seakamela, Melinda, Suchard, Marc S, Collett, Brian, Eley   +10 more
openaire   +2 more sources

Development of inactivated poliovirus vaccine derived from Sabin strains

Biologicals, 2006
In the course of Sabin-inactivated poliovirus vaccine (S-IPV) development, we have established high-yield virus production techniques based on Vero cell micro-carrier cultures. Development of specific ELISA tests to quantify the antigen content of S-IPV has been achieved.
B, Simizu, S, Abe, H, Yamamoto, Y, Tano, Y, Ota, M, Miyazawa, H, Horie, K, Satoh, K, Wakabayashi   +8 more
openaire   +2 more sources

Vaccine-derived poliovirus (VDPV): Impact on poliomyelitis eradication

Vaccine, 2009
The live attenuated strains used in the oral poliovirus (OPV) have been the main tool in the WHO polio eradication programme. However, these strains replicate in the human gut and are excreted for several weeks after immunisation. During this period, the attenuating mutations in the vaccine strains can rapidly revert.
openaire   +2 more sources

Poliomyelitis outbreaks caused by circulation of the vaccine-derived poliovirus

International Journal of Surgery, 2022
Farid Rahimi, Amin Talebi Bezmin Abadi
openaire   +2 more sources

Poliovirus Vaccine and Vaccine-Derived Polioviruses

New England Journal of Medicine, 2010
Lester M, Shulman, Yossi, Manor, Danit, Sofer   +2 more
openaire   +3 more sources

Review of use of inactivated poliovirus vaccine in campaigns to control type 2 circulating vaccine derived poliovirus (cVDPV) outbreaks

Vaccine, 2023
Concepción Estivariz
exaly  

Immune persistence of an inactivated poliovirus vaccine derived from the Sabin strain: a 10-year follow-up of a phase 3 study

EClinicalMedicine, 2023
Zhifang Ying, Zhimei Zhao
exaly