Results 11 to 20 of about 9,622 (181)

Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children. [PDF]

Nat Commun, 2023
AbstractIncreasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries previously declared polio free, is a public health emergency of international concern. Individuals with primary immunodeficiency (PID) can excrete polioviruses for prolonged periods, which could act as a source of cryptic transmission of viruses with ...
Singanayagam A, Klapsa D, Burton-Fanning S, Hand J, Wilton T, Stephens L, Mate R, Shillitoe B, Celma C, Slatter M, Flood T, Gopal R, Martin J, Zambon M.   +13 more
europepmc   +8 more sources

Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, January 2020-June 2021. [PDF]

MMWR Morb Mortal Wkly Rep, 2021
As of May 1, 2016, use of oral poliovirus vaccine (OPV) type 2 for routine and supplementary immunization activities ceased after a synchronized global switch from trivalent OPV (tOPV; containing Sabin strain types 1, 2, and 3) to bivalent OPV (bOPV; containing Sabin strain types 1 and 3) subsequent to the certified eradication of wild type poliovirus (
Alleman MM, Jorba J, Henderson E, Diop OM, Shaukat S, Traoré MA, Wiesen E, Wassilak SGF, Burns CC.   +8 more
europepmc   +5 more sources

Recombinant Vaccine–Derived Poliovirus in Madagascar

Emerging Infectious Diseases, 2003
To the Editor: Between October 2001 and April 2002, five cases of acute flaccid paralysis associated with vaccine-derived poliovirus (VDPV) type 2 isolates were reported in the southern province of the Republic of Madagascar. The first patient, an 11-year-old child from the urban district of Toliara, first experienced paralysis on October 29, 2001 ...
Dominique Rousset, Mala Rakoto-Andrianarivelo, Richter Razafindratsimandresy, Bakolalalo Randriamanalina, Sophie Guillot, Jean Balanant, Philippe Mauclère, Francis Delpeyroux   +7 more
doaj   +3 more sources

Vaccine Derived Poliovirus (VDPV). [PDF]

Infez Med, 2023
Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the Oral Polio Virus vaccine (OPV). In addition, the emergence of VDPV is one of the global challenges for the eradication of poliomyelitis.
Mohanty A, Rohilla R, Zaman K, Hada V, Dhakal S, Shah A, Padhi BK, Al-Qaim ZH, Altawfiq KJA, Tirupathi R, Sah R, Al-Tawfiq JA.   +11 more
europepmc   +3 more sources

Detection of vaccine-derived poliovirus type 2 from sewage samples and public health response, Poland, November to December 2024. [PDF]

Euro Surveill
Wieczorek M, Gad B, Krzysztoszek A, Kłosiewicz P, Oleksiak K, Zaborski B, Grzesiowski P, Tkaczuk K, Baumann-Popczyk A.   +8 more
europepmc   +2 more sources

Implications of a Circulating Vaccine-Derived Poliovirus in Nigeria [PDF]

New England Journal of Medicine, 2010
The largest recorded outbreak of a circulating vaccine-derived poliovirus (cVDPV), detected in Nigeria, provides a unique opportunity to analyze the pathogenicity of the virus, the clinical severity of the disease, and the effectiveness of control measures for cVDPVs as compared with wild-type poliovirus (WPV).We identified cases of acute flaccid ...
Helen E. Jenkins, R. Bruce Aylward, Alex Gasasira, Christl A. Donnelly, Michael Mwanza, Jukka Corander, Sandra Garnier, Claire Chauvin, Emmanuel Abanida, Muhammad Ali Pate, Festus Adu, Baba M, Nicholas C. Grassly   +12 more
openalex   +3 more sources

Monitoring the Risk of Type-2 Circulating Vaccine-Derived Poliovirus Emergence during Roll-Out of Type-2 Novel Oral Polio Vaccine [PDF]

Vaccines (Basel)
Peak CM, Lyons H, Voorman A, Gray EJ, Cooper LV, Blake IM, Hawes K, Bandyopadhyay AS.   +7 more
europepmc   +6 more sources

Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm. [PDF]

Ann Med Surg (Lond), 2022
Kamran A, Salman M, Siddiqui R, Shabbir NZ, Rohail S, Sukaina M.   +5 more
europepmc   +2 more sources

Estimating the Extent of Vaccine-Derived Poliovirus Infection

PLoS ONE, 2008
Eight outbreaks of paralytic polio attributable to circulating vaccine-derived poliovirus (cVDPV) have highlighted the risks associated with oral poliovirus vaccine (OPV) use in areas of low vaccination coverage and poor hygiene. As the Polio Eradication Initiative enters its final stages, it is important to consider the extent to which these viruses ...
Alison Wringe, Paul Fine, Roland W. Sutter, Olen M. Kew   +3 more
openalex   +5 more sources

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, July 2019–February 2020 [PDF]

MMWR. Morbidity and Mortality Weekly Report, 2020
Circulating vaccine-derived polioviruses (cVDPVs) can emerge in areas with low poliovirus immunity and cause outbreaks* of paralytic polio (1-5). Among the three types of wild poliovirus, type 2 was declared eradicated in 2015 (1,2). The use of trivalent oral poliovirus vaccine (tOPV; types 1, 2, and 3 Sabin strains) ceased in April 2016 via a 1-month ...
Mary Alleman, Jaume Jorba, Sharon A. Greene, Ousmane M. Diop, Jane Iber, Graham Tallis, Ajay Kumar Goel, Eric Wiesen, Steven G.F. Wassilak, Cara C. Burns   +9 more
openalex   +3 more sources