Results 91 to 100 of about 886,403 (306)

The global burden of cholera

open access: yesBulletin of the World Health Organization, 2012
OBJECTIVE: To estimate the global burden of cholera using population-based incidence data and reports. METHODS: Countries with a recent history of cholera were classified as endemic or non-endemic, depending on whether they had reported cholera cases in ...
Mohammad Ali   +6 more
doaj  

Nuclear-resident RIG-I senses viral replication inducing antiviral immunity

open access: yesNature Communications, 2018
RIG-I senses cytoplasmic viral RNA, resulting in induction of an antiviral response. Here, the authors identify nuclear RIG-I and show that it binds nuclear influenza A virus RNA, resulting in a cooperative interferon induction along with its cytoplasmic
GuanQun Liu   +8 more
doaj   +1 more source

Development of flow cytometry based adherence assay for Neisseria gonorrhoeae using 5′-carboxyfluorosceinsuccidyl ester

open access: yesBMC Microbiology, 2019
Background Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on the enumeration of bacteria attached to human cells on solid media.
Sidharath Dev Thakur   +4 more
doaj   +1 more source

Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania. [PDF]

open access: yes, 2012
BACKGROUND: Cervical cancer is the leading cause of female cancer-related deaths in Tanzania. Vaccination against human papillomavirus (HPV) offers a new opportunity to control this disease.
Quentin, Wilm   +9 more
core   +5 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

A Multilingual Dataset of COVID-19 Vaccination Attitudes on Twitter [PDF]

open access: yesarXiv, 2022
Vaccine hesitancy is considered as one main cause of the stagnant uptake ratio of COVID-19 vaccines in Europe and the US where vaccines are sufficiently supplied. Fast and accurate grasp of public attitudes toward vaccination is critical to address vaccine hesitancy, and social media platforms have proved to be an effective source of public opinions ...
arxiv  

HPV vaccine [PDF]

open access: yes, 2018
Human Papilloma virus has been related not only to 98% of cervical cancers but also to mouth and throat cancers. There is a vaccine that prevents contraction of this virus: HPV vaccine.
vivas, alejandra
core   +1 more source

Model evaluation of target product profiles of an infant vaccine against respiratory syncytial virus (RSV) in a developed country setting [PDF]

open access: yes, 2020
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in children worldwide and is a significant cause of hospital admissions in young children in England.
Kinyanjui, Timothy   +5 more
core   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

A highly stable lyophilized mRNA vaccine for Herpes Zoster provides potent cellular and humoral responses

open access: yesnpj Vaccines
Herpes zoster (HZ) is a painful vesicular rash that occurs upon varicella-zoster virus (VZV) reactivation in older adults and immunocompromised individuals.
Raquel Munoz-Moreno   +18 more
doaj   +1 more source

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