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Human Papillomavirus Awareness, Vaccine Status, and Risk Factors in Female Emergency Patients [PDF]
Introduction: A vaccine targeting high-risk human papillomavirus (HPV) strains can effectively prevent HPV-associated cervical cancer risk. However, many girls and women do not receive the vaccine, more often those impacted by health disparities ...
Galbraith, James W.+2 more
core
National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C+4 more
core +1 more source
Since vaccination was documented by Edward Jenner in 1798, it has become the most successful means of preventing infectious diseases, saving millions of lives every year. However, application of vaccines is currently not limited to the prevention of infectious diseases.
Jiskoot, W.+2 more
openaire +4 more sources
Vaccines, Vaccination, and Vaccinology [PDF]
Although the demonstration in 1796 by Edward Jenner that vaccinia virus could protect against smallpox was epochal, he was following the path opened by the ancients who had used the smallpox virus itself in the practice of variolation. The work of Louis Pasteur on chicken cholera opened the way to vaccine development in the laboratory.
openaire +3 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
A novel Staphylococcus aureus 4-antigen vaccine (SA4Ag) is under development, comprising capsular polysaccharide serotypes 5 and 8 (CP5 and CP8) conjugated to CRM197, recombinant protein clumping factor A (rmClfA), and recombinant manganese transporter ...
Megumi Inoue+10 more
doaj +1 more source
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Development of Middle East Respiratory Syndrome Coronavirus vaccines – advances and challenges
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an emerging pathogen with the potential to pose a threat to global public health. Sporadic cases and outbreaks continue to be reported in the Middle East, and case fatality rates remain high at ...
Heeyoun Cho+3 more
doaj +1 more source
Background: No access to safe water is an important risk factor for typhoid fever, yet risk-level heterogeneity is unaccounted for in previous global burden estimates.
Dr. Vittal Mogasale, PhD+8 more
doaj +1 more source
Introduction Vaccination is a critical tool for preventing coronavirus disease 2019 (COVID-19) and influenza illnesses. Coadministration of the COVID-19 vaccine, BNT162b2, with seasonal inactivated influenza vaccine (SIIV) can provide substantial ...
Louise Murdoch+16 more
doaj +1 more source