Results 71 to 80 of about 2,114,452 (380)

Community perceptions of a malaria vaccine in the Kintampo districts of Ghana. [PDF]

open access: yes, 2013
BACKGROUND: Malaria remains the leading cause of morbidity and mortality in sub-Saharan Africa despite tools currently available for its control. Making malaria vaccine available for routine use will be a major hallmark, but its acceptance by community ...
A Bingham   +30 more
core   +2 more sources

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

open access: yesNature Network Boston, 2021
Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization coverage to end the global pandemic, yet few studies have investigated COVID-19 vaccination attitudes in lower-income countries, where large-scale vaccination is ...
Julio S Solís Arce   +73 more
semanticscholar   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Occurrence of human infection with Salmonella Typhi in sub-Saharan Africa

open access: yesScientific Data
Typhoid fever, caused by Salmonella enterica serovar Typhi, results in over 1.2 million cases and 29 thousand deaths annually from sub-Saharan Africa. Combating this disease requires various intervention approaches, such as typhoid conjugate vaccines and
Jong-Hoon Kim   +9 more
doaj   +1 more source

Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania

open access: yesBulletin of the World Health Organization
PROBLEM: Field trials require extensive data preparation and complex logistics. The use of personal digital assistants (PDAs) can bypass many of the traditional steps that are necessary in a paper-based data entry system.
Mohammad Ali   +19 more
doaj   +1 more source

Calibration of a serum reference standard for Group B streptococcal polysaccharide conjugate vaccine development using surface plasmon resonance

open access: yesnpj Vaccines, 2023
Group B streptococcus (GBS) is a leading cause of neonatal morbidity and mortality worldwide. Development of a maternal vaccine to protect newborns through placentally transferred antibody is considered feasible based on the well-established relationship
Alexandre Esadze   +10 more
doaj   +1 more source

Serology as a Tool to Assess Infectious Disease Landscapes and Guide Public Health Policy

open access: yesPathogens, 2022
Understanding the local burden and epidemiology of infectious diseases is crucial to guide public health policy and prioritize interventions. Typically, infectious disease surveillance relies on capturing clinical cases within a healthcare system ...
Andrea H. Haselbeck   +5 more
doaj   +1 more source

Comparative analysis of the immune responses induced by native versus recombinant versions of the ASP-based vaccine against the bovine intestinal parasite Cooperia oncophora [PDF]

open access: yes, 2018
The protective capacities of a native double-domain activation-associated secreted protein (ndd-ASP)-based vaccine against the cattle intestinal nematode Cooperia oncophora has previously been demonstrated.
Borloo, Jimmy   +6 more
core   +1 more source

Vaccines

open access: yes, 2013
Since vaccination was documented by Edward Jenner in 1798, it has become the most successful means of preventing infectious diseases, saving millions of lives every year. However, application of vaccines is currently not limited to the prevention of infectious diseases.
Jiskoot, W.   +2 more
openaire   +4 more sources

Vaccines, Vaccination, and Vaccinology [PDF]

open access: yesThe Journal of Infectious Diseases, 2003
Although the demonstration in 1796 by Edward Jenner that vaccinia virus could protect against smallpox was epochal, he was following the path opened by the ancients who had used the smallpox virus itself in the practice of variolation. The work of Louis Pasteur on chicken cholera opened the way to vaccine development in the laboratory.
openaire   +3 more sources

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