Results 71 to 80 of about 1,128,358 (233)

Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]

open access: yes, 2013
The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu   +43 more
core   +5 more sources

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

open access: yesAdvanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma   +10 more
wiley   +1 more source

Tuberculosis vaccine: pipeline approaches and future prospective [PDF]

open access: yes, 2011
Tuberculosis (TB), despite anti-mycobacterial therapies and vaccine, is a deadly infectious disease with about 12 million incident cases worldwide. Existing Bacillus Calmette-Guérin (BCG) vaccine is unquestionably inexpensive, safe and effective ...
Ankita Singh   +2 more
core   +2 more sources

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel   +15 more
wiley   +1 more source

Human Papillomavirus (HPV) Vaccination Status Among University Freshmen in Hawai‘i

open access: yes, 2019
Purpose/Background: The HPV vaccine provides immunity against nine HPV strains that cause cancer and genital warts. It is recommended for 11 to 12 year olds, and catch-up immunization is recommended for females 13 to 26 years old and males 13 to 21 ...
Chen, John J.   +3 more
core  

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

Vaccines and Vaccination

open access: yesDeckerMed Medicine, 2021
Lindsey Obradovich, Nicholas C Issa
openaire   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Thermotolerance of an inactivated rabies vaccine for dogs [PDF]

open access: yes, 2016
This study provides the first robust data that the antibody response of dogs vaccinated with Nobivac® Rabies vaccine stored for several months at high temperatures (up to 30 °C) is not inferior to that of dogs vaccinated with vaccine stored under ...
Cleaveland, Sarah   +8 more
core   +1 more source

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim   +9 more
wiley   +1 more source

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