Results 81 to 90 of about 886,403 (306)

The Impact of Vaccine Hesitancy on Epidemic Spreading [PDF]

open access: yesarXiv, 2021
The COVID-19 pandemic has devastated the world in an unprecedented way, causing enormous loss of life. Time and again, public health authorities have urged people to become vaccinated to protect themselves and mitigate the spread of the disease. However, vaccine hesitancy has stalled vaccination levels in the United States.
arxiv  

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Modeling COVID-19 vaccine-induced immunological memory development and its links to antibody level and infectiousness [PDF]

open access: yesarXiv, 2022
COVID-19 vaccines have proven to be effective against SARS-CoV-2 infection. However, the dynamics of vaccine-induced immunological memory development and neutralizing antibodies generation are not fully understood, limiting vaccine development and vaccination regimen determination. Herein, we constructed a mathematical model to characterize the vaccine-
arxiv  

Evidence for cross-protection but not type-replacement over the 11 years after human papillomavirus vaccine introduction [PDF]

open access: yes, 2019
Examination of cross-protection and type replacement after human papillomavirus (HPV) vaccine introduction is essential to guide vaccination recommendations and policies.
Bernstein, David I.   +5 more
core   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

open access: yesFEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques   +5 more
wiley   +1 more source

A GMMA-CPS-Based Vaccine for Non-Typhoidal Salmonella

open access: yesVaccines, 2021
Non-typhoidal Salmonella are a major cause of gastroenteritis worldwide, as well as causing bloodstream infections in sub-Saharan Africa with a high fatality rate. No vaccine is currently available for human use.
Akosiererem S. Sokaribo   +11 more
doaj   +1 more source

Detecting Anti-Vaccine Users on Twitter [PDF]

open access: yesarXiv, 2021
Vaccine hesitancy, which has recently been driven by online narratives, significantly degrades the efficacy of vaccination strategies, such as those for COVID-19. Despite broad agreement in the medical community about the safety and efficacy of available vaccines, a large number of social media users continue to be inundated with false information ...
arxiv  

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

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