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The Structural Characterization of a Polysaccharide from the Dried Root of Salvia miltiorrhiza and Its Use as a Vaccine Adjuvant to Induce Humoral and Cellular Immune Responses. [PDF]
Int J Mol SciZhu Y +5 more
europepmc +1 more source
Isoprinosine as a foot-and-mouth disease vaccine adjuvant elicits robust host defense against viral infection through immunomodulation. [PDF]
Front Cell Infect MicrobiolKim HW +6 more
europepmc +1 more source
Past and Present Vaccinations in Sweden
Acta Paediatrica, EarlyView.
Sven Arne Silfverdal
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Developments in Vaccine Adjuvants
2021Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength and longevity of immune responses but may also influence the type of response. In this chapter, we review the adjuvants that are available for use in human vaccines, such as alum,
Firdaus, Farrhana Ziana +2 more
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Clinical Infectious Diseases, 1980
Nonreplicating, purified subunit or synthetic viral vaccines of the future are likely to be weak immunogens that will require immunopotentiation if they are to be effective. These marginal vaccines could be improved by combination with potent and safe immunologic adjuvants. The use of adjuvants should also reduce the amount of purified antigen required
openaire +2 more sources
Nonreplicating, purified subunit or synthetic viral vaccines of the future are likely to be weak immunogens that will require immunopotentiation if they are to be effective. These marginal vaccines could be improved by combination with potent and safe immunologic adjuvants. The use of adjuvants should also reduce the amount of purified antigen required
openaire +2 more sources
Seminars in Veterinary Medicine and Surgery: Small Animal, 1997
Vaccine adjuvants provide enhanced immune responses to a variety of antigens. Unlike human vaccines that are limited to aluminum-based adjuvants, veterinary vaccines may contain a large number of substances either alone or in combination that act as vaccine adjuvants.
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Vaccine adjuvants provide enhanced immune responses to a variety of antigens. Unlike human vaccines that are limited to aluminum-based adjuvants, veterinary vaccines may contain a large number of substances either alone or in combination that act as vaccine adjuvants.
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Immunology of Vaccine Adjuvants
2009In recent times vaccine adjuvants, or immunopotentiators, received abundant attention in the media as critical ingredients of current and future vaccines. Indeed, vaccine adjuvants are recognized to make the difference between competing vaccines based on identical antigens.
Ribeiro, C.M.S., Schijns, V.E.J.C.
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Current Opinion in HIV and AIDS, 2016
Advances in the understanding of the structural biology of HIV-1 proteins, and in the vulnerabilities of HIV-1 at various points in the infectious process have led to innovative approaches for vaccine constructs for clinical trials. Lessons from the successful Retrovirology study 144 (RV144) phase III Thai trial have revealed the need for novel and ...
Mangala, Rao, Carl R, Alving
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Advances in the understanding of the structural biology of HIV-1 proteins, and in the vulnerabilities of HIV-1 at various points in the infectious process have led to innovative approaches for vaccine constructs for clinical trials. Lessons from the successful Retrovirology study 144 (RV144) phase III Thai trial have revealed the need for novel and ...
Mangala, Rao, Carl R, Alving
openaire +2 more sources
BioDrugs, 2000
Adjuvanted influenza vaccine is composed of 2 type A and 1 type B inactivated influenza subunits combined with an oil-and-water emulsion (MF59). Each dose contains 15microg haemagglutinin per strain. Adjuvanted influenza vaccine was immunogenic in elderly vaccinees and in younger adults after 1 to 3 consecutive annual injections.
M, Dooley, K L, Goa
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Adjuvanted influenza vaccine is composed of 2 type A and 1 type B inactivated influenza subunits combined with an oil-and-water emulsion (MF59). Each dose contains 15microg haemagglutinin per strain. Adjuvanted influenza vaccine was immunogenic in elderly vaccinees and in younger adults after 1 to 3 consecutive annual injections.
M, Dooley, K L, Goa
openaire +2 more sources