Results 261 to 270 of about 545,826 (308)

Polysaccharides as vaccine adjuvants

Vaccine, 2018
Adjuvant is a substance added to vaccine to improve the immunogenicity of antigens, and it can induce stronger immune responses and reduce the dosage and production cost of vaccine in populations responding poorly to vaccination. Adjuvants in development or in use mainly include aluminum salts, oil emulsions, saponins, immune-stimulating complexes ...
Beini, Sun, Shuang, Yu, Dongying, Zhao, Sihan, Guo, Xiaohua, Wang, Kai, Zhao   +5 more
openaire   +2 more sources

The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine

Vaccine, 2001
Elderly people and subjects with underlying chronic diseases are at increased risk for influenza and related complications. Conventional influenza vaccines provide only limited protection in the elderly population. In order to enhance the immune response to influenza vaccines, several adjuvants have been evaluated. Among these, an oil in water adjuvant
openaire   +2 more sources

Adjuvants for malaria vaccines

Parasite Immunology, 2009
SummaryThere is a renewed enthusiasm about subunit vaccines for malaria coincident with the formation of new alliances and partnerships raising international public awareness, attracting increased resources and the re‐focusing of research programs on adjuvant development for infectious disease vaccines.
R N, Coler, D, Carter, M, Friede, S G, Reed   +3 more
openaire   +2 more sources

Adjuvants in influenza vaccines

Vaccine, 2012
The effectiveness of influenza vaccines is still controversial, and the role of adjuvants in such vaccines is briefly reviewed in this paper. Inactivated whole virus vaccines may include components that function as adjuvants, meaning that additive adjuvants are often not required. MF59 and AS03 showed higher adjuvanticity than aluminum salts in several
Kohhei, Tetsutani, Ken J, Ishii
openaire   +2 more sources

Vaccine adjuvants revisited

Vaccine, 2007
The development of new adjuvants for human vaccines has become an expanding field of research in the last thirty years, for generating stronger vaccines capable of inducing protective and long-lasting immunity in humans. Instead of such efforts, with several adjuvant strategies approaching to requirements for their clinical application, limitations ...
J C, Aguilar, E G, Rodríguez
openaire   +2 more sources

Nanoparticles as Adjuvants for Vaccines

1995
PMMA nanoparticle adjuvants can be manufactured in a physicochemically reproducible manner. Their particle size can be controlled within narrow limits. Immunogens may be either incorporated or adsorbed to these nanoparticles. PMMA nanoparticles induced significantly higher and more prolonged antibody responses against a variety of immunogens, including
openaire   +2 more sources

Adjuvants for Animal Vaccines

Viral Immunology, 2018
Vaccines are essential tools for the prevention and control of infectious diseases in animals. One of the most important steps in vaccine development is the selection of a suitable adjuvant. The focus of this review is the adjuvants used in vaccines for animals.
Yulia, Burakova, Rachel, Madera, Scott, McVey, John R, Schlup, Jishu, Shi   +4 more
openaire   +2 more sources

Adjuvants for vaccines, a quest

International Immunopharmacology, 2003
Efficient vaccines comprise a specific moiety: the structures presenting the protective antigenic determinants, and a nonspecific moiety: the adjuvant components. Dramatic advances have been reported concerning the specific moiety and new and highly purified immunogens have been defined and prepared.
openaire   +2 more sources

Recent advances on chitosan as an adjuvant for vaccine delivery

International Journal of Biological Macromolecules, 2022
Nazrul Islam, Isra' Dmour
exaly  

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Cell, 2018
Haitao Wu, Haiteng Deng, Eric Oldfield   +2 more
exaly