Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila +12 more
wiley +1 more source
A novel cross-species vaccine design and nasal immunization strategy based on recombinant <i>Lactiplantibacillus plantarum</i> expressing PEDV tS1. [PDF]
Hao J +5 more
europepmc +1 more source
Harnessing epitope reciprocity and multimeric epitope density for a novel multiepitope vaccine design against Acinetobacter baumannii. [PDF]
Rahbar MR +4 more
europepmc +1 more source
T-Cell-Based Universal Dengue Vaccine Design for Robust Protective Response. [PDF]
Sun YF, Yeo Syin Lian A, Moi ML.
europepmc +1 more source
B-vac a robust software package for bacterial vaccine design. [PDF]
Ali A +4 more
europepmc +1 more source
Comprehensive profiling of alternative splicing and immune landscapes in rectal cancer: implications for mRNA vaccine design and immune subtype stratification. [PDF]
Weng J +5 more
europepmc +1 more source
Protective and pathogenic antibody responses from a primate Shigella outbreak inform vaccine design
Gallant RM +19 more
europepmc +1 more source
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Vaccines and Immunoinformatics for Vaccine Design
2022The host immune system recognizes and responds to the selective antigens or epitopes (immunome) of the intruding pathogen over an entire organism. The immune response so generated is ample to confer the desired immunity and protection to the host. This led to the conception of immunome-derived vaccines that exploit selective genome-derived antigens or ...
Shikha, Joon +2 more
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