Results 261 to 270 of about 26,123,489 (353)
Comprehensive genomic and computational insights into Brucella suis: pan-genome analysis, evolutionary perspectives, and in-silico vaccine design. [PDF]
Asif GMSU +13 more
europepmc +1 more source
Risk management externalities in agrifood supply chains
Abstract Firms may under‐ or over‐invest in risk management from the social planner's perspective, resulting in a negative externality on other economic agents in the supply chain. The externality of risk management is particularly relevant for agrifood supply chains, which frequently experience disruptions and play a primary role in preventing major ...
Jeffrey Hadachek, Meilin Ma
wiley +1 more source
dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng +7 more
wiley +2 more sources
Fc effector functions in RNA viral infections: mechanisms of antiviral immunity and implications for vaccine design. [PDF]
Zhang J +9 more
europepmc +1 more source
ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz +13 more
wiley +1 more source
Mechanisms of Norovirus Immunity: Implications for Vaccine Design. [PDF]
Ökten AB, Craft JE, Wilen CB.
europepmc +1 more source
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir +6 more
wiley +1 more source
Adaptation of a Fluorogenic RNA to N1‐Methylpseudouridine Nucleoside Chemistry
Several green‐emitting fluorogenic RNA aptamers were evaluated following the replacement of every uridine by N1‐methylpseudouridine (mΨ). Because this modification impaired the function of most aptamers, a directed evolution strategy combining droplet microfluidics, bioinformatics, and rational design was used to identify an aptamer preserving its ...
Patrick P.A. Bertrand +4 more
wiley +2 more sources
How <i>Mycobacterium tuberculosis</i> Subverts Innate and Adaptive Immunity and Their Crosstalk: Implications for Vaccine Design. [PDF]
Prasad GVRK, Philips JA.
europepmc +1 more source

