Results 271 to 280 of about 26,123,489 (353)

Non-Coding DNA-Derived Mimotopes of Aβ₄₂ as Novel Candidates for Alzheimer's Peptide Vaccine Design. [PDF]

Int J Med Sci
Raj N, R SP, Ammar RB, Rajendran P, Chellappan BV.   +4 more
europepmc   +1 more source

Understanding the impact of Klebsiella pneumoniae K-Antigen based MAPS vaccine design on the immune response in animal models. [PDF]

PLoS Pathog
Palmieri E, Belciug GF, Nonne F, Massai L, Valensin S, De Rosa A, Berlanda Scorza F, Rondini S, Carducci M, Rossi O, Micoli F, Giannelli C.   +11 more
europepmc   +1 more source

Correction: Immunoinformatics-driven multi-epitope vaccine design targeting PSMA, STEAP1, and B7H3 for prostate cancer. [PDF]

Front Med (Lausanne)
Runtunuwu SVBE, Tallei TE, Kim HJ, Park MN, Celik I, Kirilmaz B, Turalaki GLA, Fatimawali F, Tendean LEN, Kaseke MM, Makawaehe DR, Rambi EV, Kim B.   +12 more
europepmc   +1 more source

Author Correction: Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design. [PDF]

Nat Commun
He L, Lee YZ, Zhang YN, Newby ML, Janus BM, Gonzalez FG, Ward G, DesRoberts C, Hung SH, Giang E, Allen JD, Kulakova L, Toth EA, Fuerst TR, Law M, Ofek G, Crispin M, Zhu J.   +17 more
europepmc   +1 more source

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

Angewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber, Caroline T. Holick, Lucas Gath, Ekaterina Tsarenko, Vivien Bachmann, Stavroula Litsiou, Lukas Harder, Laura J. Rosenberger, Aleksandar Rusevski, Julian Kimmig, Stephan Culemann, Christian Franke, Claudia Waskow, Stephanie Hoeppener, Stephanie Schubert, Matthias Bros, Oliver Werz, Ivo Nischang, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +21 more
wiley   +1 more source

Immunogenicity of poxvirus A16/G9 entry-fusion subcomplex and its restriction by A56/K2 protein informs vaccine design. [PDF]

Nat Microbiol
Yu H, Resch W, Cotter CA, Xiao W, Karamanolis T, Belghith AA, Ignacio MA, Earl PL, Cohen GH, Moss B.   +9 more
europepmc   +1 more source

Cryo-EM structure of African horse sickness virus VP2 receptor-binding protein enables nanoparticle vaccine design. [PDF]

Nat Commun
Martínez-Castillo A, Aebischer A, Toneatti P, Fu L, Vitour D, Sailleau C, Hoffmann B, Franzke K, Eschbaumer M, Weber S, Calvo Pinilla E, Ortego J, Gil-Cartón D, Bréard E, Zientara S, Kortekaas J, Beer M, Abrescia NG.   +17 more
europepmc   +1 more source

Systematic characterization of SARS-CoV-2 spike protein subunit trafficking and secretion reveals enhanced strategies for vaccine design and quantification. [PDF]

Front Microbiol
Zhang Q, Hammond M, Song J, Fang Z, Zhao H, Landström M, Mei YF.   +6 more
europepmc   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

Angewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer, Kathrin Halter, Chun‐Yin Chan, Thomas Carell   +3 more
wiley   +1 more source

From Innate to Adaptive: Paradigm Shifts and Frontier Challenges in Next-Generation Vaccine Design. [PDF]

Vaccines (Basel)
Huang S, Yu S, Zhang M, Huang Y, Tian B, Lu J, Lu J.   +6 more
europepmc   +1 more source