Results 291 to 300 of about 26,123,489 (353)

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel, Zoe Swank, Jiaqi Wang, Xiaosong Wang, Lauren A. O'Keeffe, Madison Negron, Liya S. Getachew, Louise L. Hansen, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie A. Davis, Kathleen M. M. Vanni, Sandria Savage, Julie S. Lam, Zachary S. Wallace, David R. Walt, Jeffrey A. Sparks, on behalf of RECOVER‐Adult   +18 more
wiley   +1 more source

A single residue in the VP3 capsid protein governs virulence and informs live-attenuated vaccine design for coxsackievirus A6. [PDF]

J Virol
Liu K, Liu Z, Yan X, Yang Z, Li X, Zhang C.   +5 more
europepmc   +1 more source

Proteome-wide curation of experimentally validated HPV T-cell epitopes identifies key gaps in our understanding of cellular immunity to HPV and informs vaccine design. [PDF]

Front Immunol
Putra SP, Cankat S, Swadling L.
europepmc   +1 more source

Receptor binding domain-independent pancoronavirus vaccine design by fusion of conserved T/B Epitopes. [PDF]

Emerg Microbes Infect
Yang Y, Chen Y, Hong M, Zou R, Yao J, Li E, Wang J, Ye X, Xing Y, Tang Y, Lu X, Ding C, He H, Tong D, Shang Y, Wang J, Zhao G, Huang X, Feng F, Cheng Q, Li B, Huang B, Tan W, Chiu S, Jin T.   +24 more
europepmc   +1 more source

Universal broad-spectrum mucosal vaccine design for human coronaviruses inspired by artificial antibodies. [PDF]

NPJ Vaccines
Wu Y, Lu J, Fang L, Chen X, Zhao C, Zhang Z, Zhu X, Gao X, Li H, Yan Y, Shi J, Zhang J, Zhou P, Pan X.   +13 more
europepmc   +1 more source

Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells

npj Vaccines
Julie Zimmermann, Simon D. van Haren, Joann Diray-Arce, Ignatius Ryan Adriawan, Katharina Wørzner, Ricki T. Krog, Safia Guleed, Tu Hu, Rasmus Mortensen, Jes Dietrich, Sara M. Ø. Solbak, Ofer Levy, Dennis Christensen, Gabriel K. Pedersen   +13 more
doaj   +1 more source

From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges. [PDF]

Front Syst Biol
De Lima Coelho NS, De Lima Coelho VS.
europepmc   +1 more source

Protective and pathogenic antibody responses from a primate Shigella outbreak inform vaccine design

Gallant RM, Savarino P, Pulido S, Gilman M, Lu T, Hayes J, Xerri NL, Williams T, Ochoa MA, Dietz Z, Peterson E, Scott T, Hartmann F, Baker SG, Kaminski RW, Sok D, Kruse AC, Picking W, Capuano SV, Schmidt HR.   +19 more
europepmc   +1 more source

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Vaccines and Immunoinformatics for Vaccine Design

2022
The host immune system recognizes and responds to the selective antigens or epitopes (immunome) of the intruding pathogen over an entire organism. The immune response so generated is ample to confer the desired immunity and protection to the host. This led to the conception of immunome-derived vaccines that exploit selective genome-derived antigens or ...
Shikha, Joon, Rajeev K, Singla, Bairong, Shen   +2 more
openaire   +2 more sources

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy.

Advanced Drug Delivery Reviews, 2022
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for the development of vaccines and immunotherapeutic strategies against infectious and noninfectious diseases.
Qiong Long, Peng Zheng, Xiao Zheng, Weiran Li, Liangqun Hua, Zhong-Qian Yang, Wei-Wei Huang, Yan-Bing Ma   +7 more
semanticscholar   +1 more source