Results 311 to 320 of about 26,123,489 (353)
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DCs as targets for vaccine design
Cytotherapy, 2004The increasingly stringent requirements laid down by regulatory authorities have brought to an end the largely empirical design of vaccines. Vaccines must now be designed rationally, in order that appropriate immune responses are elicited with few or no side effects.
Belz, Gabrielle T. +4 more
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2006
The purpose of this chapter is to present basic strategies for the construction of DNA vaccines. This chapter discusses considerations relevant to the selection of a target gene, construction of a DNA expression vector for use as a vaccine, and molecular modifications of the vector to improve protein expression and to augment immunogenicity.
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The purpose of this chapter is to present basic strategies for the construction of DNA vaccines. This chapter discusses considerations relevant to the selection of a target gene, construction of a DNA expression vector for use as a vaccine, and molecular modifications of the vector to improve protein expression and to augment immunogenicity.
openaire +2 more sources
Design of peptide and polypeptide vaccines
Current Opinion in Biotechnology, 1997Advances have been made in the development of vaccines based on synthetic peptides and polypeptides representing tumor-associated antigens and protective epitopes of viruses and parasites. Advances within the past year include the design of vaccines based on artificial proteins, for example multiantigen peptides, branched polypeptides, fusion and ...
T, Ben-Yedidia, R, Arnon
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Biomimetic design in microparticulate vaccines
Biomaterials, 2003Current efforts to improve the effectiveness of microparticle vaccines include incorporating biomimetic features into the particles. Many pathogens use surface molecules to target specific cell types in the gut for host invasion. This observation has inspired efforts to chemically conjugate cell-type targeting ligands to the surfaces of microparticles ...
Mark E, Keegan +2 more
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Molecular Structure and Vaccine Design
Annual Review of Biophysics and Biophysical Chemistry, 1990CONTENTS PERSPECTIVES AND OVERVIEW • . . . . . .... 70 The Molecules: a Brief Review . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Two Strategies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
S, Vajda +5 more
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Artificial Intelligence for Vaccine Design.
Methods in molecular biology, 2021P. McCaffrey
semanticscholar +1 more source
Trends in Microbiology, 1993
O ver the past decade, the revolution in molecular and structural biology has opened up the immune system to detailed analysis. The genes encoding critical molecules of the immune system have been identified and the structure of these genes has been determined.
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O ver the past decade, the revolution in molecular and structural biology has opened up the immune system to detailed analysis. The genes encoding critical molecules of the immune system have been identified and the structure of these genes has been determined.
openaire +2 more sources
Why Young Patients With Cancer Refuse the Human Papillomavirus Vaccine
Ca-A Cancer Journal for Clinicians, 2023Mike Fillon
exaly