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Developments in Vaccine Adjuvants
2021Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength and longevity of immune responses but may also influence the type of response. In this chapter, we review the adjuvants that are available for use in human vaccines, such as alum,
Firdaus, Farrhana Ziana +2 more
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Carbohydrates in Vaccine Development
Current Drug Delivery, 2019Despite advances in the development of new vaccines, there are still some diseases with no vaccine solutions. Therefore, further efforts are required to more comprehensively discern the different antigenic components of these microorganisms on a molecular level.
Aljohani, Salwa +3 more
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Pediatric Clinics of North America
This article considers ethical considerations surrounding pediatric vaccine development for pandemic preparedness, examines some historical cases of pediatric vaccines developed during past smallpox, influenza, and 2019 coronavirus disease pandemics, and discusses the current state of vaccine development for pandemic preparedness, including vaccines ...
Elizabeth A D, Hammershaimb +1 more
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This article considers ethical considerations surrounding pediatric vaccine development for pandemic preparedness, examines some historical cases of pediatric vaccines developed during past smallpox, influenza, and 2019 coronavirus disease pandemics, and discusses the current state of vaccine development for pandemic preparedness, including vaccines ...
Elizabeth A D, Hammershaimb +1 more
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The future of vaccine development
Vaccine, 2020Vaccines are one of the most successful public health interventions in our history resulting in eradication of small pox, near eradication of polio and major reductions in case number and global morbidity and mortality for numerous diseases (Centers for Disease C, 1999) [1].
Wayne C, Koff, Theodore, Schenkelberg
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Contraceptive vaccine development
Reproduction, Fertility and Development, 1994Recent advances in antigen definition and production have made the development of a contraceptive vaccine more attainable. Such a vaccine must evoke an immune response that blocks an indispensable step in the reproductive process. Vaccine research involves many approaches to fertility prevention.
N J, Alexander, G, Bialy
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Meningococcal Vaccines and Vaccine Developments
2003Despite rapid advances in the diagnosis of bacterial infections and the availability of effective antibiotics, meningococcal disease continues to represent a substantial public health problem for most countries (1-4). Disease usually develops rapidly, is notoriously difficult to distinguish from other febrile illnesses, and generally has a high case ...
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Biotechnology of Vaccine Development
Biotechnology and Genetic Engineering Reviews, 1990(1990). Biotechnology of Vaccine Development. Biotechnology and Genetic Engineering Reviews: Vol. 8, No. 1, pp. 53-96.
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Development of combination vaccines
Vaccine, 1999Breakthroughs in molecular biology, biochemistry, process development, immunology and related fields have provided the means for improving current vaccines and developing new ones. The increasing availability of these vaccines is providing the unprecedented opportunity to prevent serious infectious disease in different age groups and to significantly ...
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Tuberculosis vaccine development
Current Opinion in Pulmonary Medicine, 2002If the end of the 20th century saw the flowering of genomics, the beginning of the 21st century is witnessing an equally rapid blossoming of proteomics. These twin technologies have had a dramatic influence on the study of tuberculosis (TB), and nowhere more so than in the development of new TB vaccines.
T Mark, Doherty, Peter, Andersen
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Genomics and vaccine development.
Revue scientifique et technique (International Office of Epizootics), 2007The current explosion in new high-throughput technologies arising from microbial and animal genomics studies is enabling the analysis of the genome, transcriptome, and proteome and offers the opportunity to gain a better understanding of the molecular pathways underlying pathogen biology, the host immune system, and host-pathogen interactions.
Gay, Cyril +6 more
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