Results 211 to 220 of about 389,573 (268)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Advances in fungal vaccine development: Progress in the face of emerging challenges. [PDF]

iScience
Moses M, Huang X, Xue X, Chen C.
europepmc   +1 more source

Immune Aspects of Clostridioides difficile Infection and Vaccine Development. [PDF]

Infect Dis Clin North Am
Glover RC, Peritore-Galve FC, Lacy B, Zackular JP.   +3 more
europepmc   +1 more source

Light‐Activated Isolation of High‐Quality Mitochondria for Therapeutic Transplantation

Angewandte Chemie, EarlyView.
The Light‐Activated Mitochondrial Isolation (LAMI) platform enables the selective and non‐destructive isolation of high‐purity, metabolically active mitochondria. By integrating modular, ligand‐programmable magnetic probes with photo‐cleavable release, LAMI overcomes long‐standing limitations of conventional isolation methods and provides a robust ...
Hui Liu, Yuxin Jiao, Ting Zhang, Haiwei Wang, Yufei Xue, Jiayu Ding, Yang Ding, Meiling Wang, Weisen Zhang, Hua Bai, Bo Peng, Nicolas H. Voelcker, Lin Li   +12 more
wiley   +1 more source

One-component ionizable amphiphilic Janus dendrimers as a delivery platform for efficient mRNA vaccine development. [PDF]

Sci Adv
Ona NA, Zhang D, Lindesmith LC, Park WJ, Meshanni JA, Berkihiser S, Vasserman JA, Toshtzar S, Moore NC, Williams B, Nakagawa B, Baboo I, Pan L, Cheng W, Mercado-López X, Bonilla-Acosta W, Brewer-Jensen PD, Zweigart MR, Reyes YI, Mallory ML, May SR, Zhou Y, Percec V, Baric RS, Li Y, Weissman D, Atochina-Vasserman EN.   +26 more
europepmc   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

Angewandte Chemie, EarlyView.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang, Pierre Mesdom, Eduardo Izquierdo‐García, João P. M. António, Ruonan Gao, Bruno Saubaméa, Johanne Seguin, Morgane Moinard, Philippe Arnoux, Céline Frochot, Kevin Cariou, Bich‐Thuy Doan, Gilles Gasser   +12 more
wiley   +1 more source

Current Status and Challenges of Vaccine Development for Seasonal Human Coronaviruses. [PDF]

Vaccines (Basel)
Zhang B, Liu Y, Chen T, Lai J, Liu S, Liu X, Zhu Y, Rao H, Peng H, Ma X.   +9 more
europepmc   +1 more source

Advances and Translational Challenges in <i>Toxoplasma gondii</i> Vaccine Development: From Antigen Discovery to mRNA and One Health Strategies. [PDF]

Vet Sci
Qadeer A, Tharwat M, Khan MZ, Juhasz A, Alshanbari FA.   +4 more
europepmc   +1 more source

Role of Donor Unrestricted T Cells (DURTs) in TB Host Defense: Implications for Novel TB Vaccine Development. [PDF]

Vaccines (Basel)
Kain D, Lewinsohn DM, Lewinsohn DA.
europepmc   +1 more source

Vaccine development against <i>Mycobacterium tuberculosis</i>: a PRISMA-guided systematic review of conventional and computational multi-epitope approaches. [PDF]

Clin Exp Vaccine Res
Akbar EA, Tukiran T, Sanjaya IGM, Agustini R, Sidiq MN.   +4 more
europepmc   +1 more source