Results 231 to 240 of about 15,392,732 (265)
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Development of vaccines for coccidioidomycosis
Mycopathologia et Mycologia Applicata, 1970A most compelling stimulus to investigate the influence of actively-induced immunity in experimental coccidioidomycosis is found in the epidemiologic studies ofSmith (35) andSmith et al. (37–39). Their serologic and skin test surveys among residents in areas of coccidioidal endemicity directed attention to a role apparently played by actively-acquired ...
H B, Levine, D, Pappagianis, J M, Cobb
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Development of babesial vaccines
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1989The most widely used vaccine against cattle babesiosis was blood from a carrier animal. The development of a calf passage attenuated strain in Australia was a great improvement in vaccine safety and efficacy. The degree of immunity generated by this vaccine remains a standard against which to compare other vaccines.
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Development of sporozoite vaccines
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984Abstract Protective immunity against m alaria has been achieved in hosts ranging from birds to man by repeated inoculation of irradiated sporozoites. The main antigens involved in protective immunity to sporozoites are the circumsporozoite (CS) proteins, which are part of a family of proteins, covering the whole surface mem brane of ...
R S, Nussenzweig, V, Nussenzweig
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Frontiers in Bioscience, 2005
For the past two decades, scientists have aggressively pursued the development of a vaccine against human immunodeficiency virus (HIV). The magnitude of this effort is unprecedented in the history of infectious diseases. However, difficulties in finding promising candidate vaccines have limited the number of clinical efficacy trials.
Mahender, Singh +2 more
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For the past two decades, scientists have aggressively pursued the development of a vaccine against human immunodeficiency virus (HIV). The magnitude of this effort is unprecedented in the history of infectious diseases. However, difficulties in finding promising candidate vaccines have limited the number of clinical efficacy trials.
Mahender, Singh +2 more
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Malaria vaccines in development
Expert Opinion on Emerging Drugs, 2005The recent infusion of public and private funding for malaria vaccine development has greatly accelerated the pace at which candidate malaria vaccines are entering the clinic. Recent promising results from vaccine trials carried out in malaria-naive and -endemic populations have revealed important insights into what will be required of a successful ...
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Vaccine development reconsidered
Vaccine, 1988This paper briefly reviews work on vaccine development since the early 1950s with special emphasis on identification of immunogens and their presentation to the host so as to elicit an immune response. This is illustrated primarily by a discussion of the development of a candidate meningococcal B vaccine based on a capsular carbohydrate outer membrane ...
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Development of a sporozoite vaccine
Parasitology Today, 1985R S, Nussenzweig, V, Nussenzweig
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