Results 201 to 210 of about 435,241 (348)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Helminthic Infections and Vaccine Efficacy in Cattle: Implications for Disease Control and Sustainable Livestock Production. [PDF]

Vet Sci
Freire T, Capozzo AV.
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Long-Term Efficacy of a Hepatitis E Vaccine [PDF]

, 2015
Jun Zhang, Xuefeng Zhang, Shoujie Huang, Ting Wu, Yuemei Hu, Zhongze Wang, Hua Wang, Han-Min Jiang, Yijun Wang, Qiang Yan, Meng Guo, Xiaohui Liu, Jingxin Li, Changlin Yang, Quan Tang, Renjie Jiang, Huirong Pan, Yimin Li, J. Wai‐Kuo Shih, Mun‐Hon Ng, Fengcai Zhu, Ningshao Xia   +21 more
openalex   +1 more source

Modulation of oral vaccine efficacy by the gut microbiota. [PDF]

NPJ Vaccines
Hou Y, Li J, Wu Y.
europepmc   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Supplementary Methods, Figure Legends from Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

, 2023
Laura Jeanbart, Marie Ballester, Alexandre de Titta, Patricia Corthésy, Pedro Romero, Jeffrey A. Hubbell, Melody A. Swartz   +6 more
openalex   +1 more source

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

Advanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen, Jingrui Zhong, Xiaochun Zhang, Jingke Chen, Lin Guo, Xiaoliang Xiong, Xiaonan Zhang, Xiangyu Liu, Bailong Xiao, Boxue Tian   +9 more
wiley   +1 more source

Data Sheet 1_Probiotic peptidoglycan skeleton enhances vaccine efficacy against MRSA by inducing trained immunity via the TLR2/JAK-STAT3 pathway.docx

Lingdi Niu (18594982), Haoyuan Duan (18594991), Jiaqing Wang (1542784), Zheng Jia (1861600), Hai Li (254910), Junjie Guo (758456), Shuhe Zhang (6294701), Ning Liu (168279), Yaxin Miao (9417700), Junwei Ge (14518817), Fang Wang (105926)   +10 more
openalex   +1 more source

A new approach to estimate vaccine efficacy based on immunogenicity data applied to influenza vaccines administered by the intradermal or intramuscular routes [PDF]

, 2010
Laurent Coudeville, Philippe André, Fabrice Bailleux, Françoise Weber, Stanley A. Plotkin   +4 more
openalex   +1 more source