Results 211 to 220 of about 435,241 (348)

Data from Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

, 2023
Laura Jeanbart, Marie Ballester, Alexandre de Titta, Patricia Corthésy, Pedro Romero, Jeffrey A. Hubbell, Melody A. Swartz   +6 more
openalex   +1 more source

Type I interferon restricts mRNA vaccine efficacy through suppression of antigen uptake in cDCs. [PDF]

NPJ Vaccines
Lobb TA, Dickson A, Guo W, Beeram S, Carrero JA, Dalben Y, DiPaolo RJ, Alspach E, Tse LV, Ferris ST.   +9 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

A narrative review of heterogeneity in SARS-CoV-2 infection outcomes and vaccine efficacy: strategizing pandemic preparedness in Africa. [PDF]

Front Public Health
Kerai T, Woolhouse M, Nyazema NZ, Mutapi F.   +3 more
europepmc   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Safety and efficacy of a thymidine kinase negative equine herpesvirus-1 vaccine in young horses.

, 1990
Janyce Louise Cornick, Judy G. Martens, Ronald J. Martens, Robert A. Crandell, Stewart McConnell, Saul Kit   +5 more
openalex   +1 more source

Evaluation of the efficacy of hepatitis B vaccine in different age groups of vaccinated children in Egypt

, 2016
Ahmed Mohamed Tammam Abdelgawad, Abdelmoneam Hosni   +1 more
openalex   +1 more source

Overview of the Main Anti-SARS-CoV-2 Vaccines: Mechanism of Action, Efficacy and Safety

, 2021
Maria Teresa Mascellino, Federica Di Timoteo, Massimiliano De Angelis, Alessandra Oliva   +3 more
openalex   +2 more sources

A Systematic Review and Meta-Analysis of Porcine Epidemic Diarrhea Virus Vaccine Efficacy and Its Modifiers. [PDF]

Animals (Basel)
Li S, Niu S, Yao B, Chen Q, Ma W, Luo J, Zheng H, Xu G, Wu T, Yao W, Yang L, Fu L.   +11 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source