Results 71 to 80 of about 2,076,500 (256)

Why did people refuse vaccination during the pandemic? Exploring the impacts of trust and vaccine risk perception on COVID-19 vaccine hesitancy in China

open access: yesFrontiers in Public Health
BackgroundVaccination was a critical step in combating the COVID-19 outbreak, but vaccine hesitancy was a prominent global concern in the pandemic. In China, the behavior of vaccination might be affected by the past vaccine-related scandals.ObjectiveThis
Dan Huang, Yi Wu, Hui Li
doaj   +1 more source

Intention-to-prevent analyses for estimating human papillomavirus vaccine efficacy in clinical studies

open access: yesContemporary Clinical Trials Communications, 2017
HPV vaccine efficacy trials have been conducted in populations exposed to HPV infection (i.e., sexually active individuals); participants were not excluded from participating in the trials based on their HPV status at baseline.
Alfred Saah   +3 more
doaj   +1 more source

Single dose of SA 14-14-2 vaccine provides long-term protection against Japanese encephalitis: A case-control study in Nepalese children 5 years after immunization

open access: yes, 2007
In July 1999, a single dose of live-attenuated SA 14-14-2 Japanese encephalitis (JE) vaccine was administered to children living in the Bardiya, Banke and Kailali districts of Nepal.
오희철, 남정모
core   +1 more source

A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults. [PDF]

open access: yes, 2004
BACKGROUND: Many malaria vaccines are currently in development, although very few have been evaluated for efficacy in the field. Plasmodium falciparum multiple epitope (ME)- thrombospondin-related adhesion protein (TRAP) candidate vaccines are designed ...
Greenwood, Brian M   +55 more
core   +2 more sources

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki   +7 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Efficacy and safety of vaccines to prevent respiratory syncytial virus infection in infants and older adults: A systematic review and meta-analysis

open access: yesInternational Journal of Infectious Diseases
Objectives: To determine the efficacy and safety of respiratory syncytial virus (RSV) vaccines in infants and older adults. Methods: We performed a systematic review and meta-analysis of randomized control trials that evaluated the efficacy of maternal ...
Baoqi Zeng   +5 more
doaj   +1 more source

Using simulation to estimate the power of a badger vaccine trial [PDF]

open access: yes, 2011
The aim of this study was to estimate the power of a badger vaccine field trial using simulation techniques. The effects of sample size, sensitivity and specificity of the diagnostic test, transmission rate between unvaccinated badgers, Vaccine Efficacy ...
Aznar, I.   +3 more
core  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

A predictive model for rapid assessment of protective efficacy against emerging SARS-CoV-2 variants

open access: yesInfectious Disease Modelling
An effective predictive model of protection would be very helpful to provide a timely and reliable evaluation of the vaccine induced protection against corresponding to rapidly emerging evolving SARS-CoV-2 variants.
Lairun Jin   +5 more
doaj   +1 more source

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