Results 141 to 150 of about 255,990 (266)

Pregnancy reduces COVID-19 vaccine immunity against novel variants. [PDF]

NPJ Vaccines
Parish MA, Sachithanandham J, Gutierrez L, Park HS, Yin A, Roznik K, Creisher P, Lee JS, St Clair LA, Werner A, Pilgrim-Grayson C, Berhane L, Golding H, Shea P, Fenstermacher K, Rothman R, Burd I, Sheffield J, Cox AL, Pekosz A, Klein SL.   +20 more
europepmc   +1 more source

Morphology of Lymphoid Tissue in the Lungs of Guinea Pigs Infected with Mycobacterium bovis against the Background of Vaccine Immunity and the Action of Betulin and Its Derivatives. [PDF]

Vaccines (Basel), 2022
Koshkin IN, Vlasenko VS, Pleshakova VI, Alkhimova LE, Elyshev AV, Kulakov IV.   +5 more
europepmc   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

Angewandte Chemie, EarlyView.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang, Pierre Mesdom, Eduardo Izquierdo‐García, João P. M. António, Ruonan Gao, Bruno Saubaméa, Johanne Seguin, Morgane Moinard, Philippe Arnoux, Céline Frochot, Kevin Cariou, Bich‐Thuy Doan, Gilles Gasser   +12 more
wiley   +2 more sources

Ginsenoside Rh2-Liposome Potentiate Vaccine Immunity through Enhanced MHC‑I Presentation. [PDF]

ACS Omega
Nie Q, Chen Z, Gong W, Cao W, Wang X, Liu Y, Zhang S, Yang Y, Meng Z.   +8 more
europepmc   +1 more source

Predicting the Effects of Waning Vaccine Immunity Against COVID-19 through High-Resolution Agent-Based Modeling. [PDF]

Adv Theory Simul, 2022
Truszkowska A, Zino L, Butail S, Caroppo E, Jiang ZP, Rizzo A, Porfiri M.   +6 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Vaccine immunity in patients with 22q11.2 microdeletion syndrome. [PDF]

Pediatr Allergy Immunol
Farpour L, Gualtieri R, Kotalova T, Lemaître B, Ducreux J, Arm-Vernez I, Eliez S, Blanchard-Rohner G.   +7 more
europepmc   +1 more source

SARS-CoV-2 Variants in COVID-19 Disease: A Focus on Disease Severity and Vaccine Immunity in Patients Admitted to the Emergency Department. [PDF]

J Pers Med, 2022
Fogolari M, Francesconi M, De Florio L, Giovanetti M, Veralli R, De Flora C, Maruotti A, Scarpa F, Spoto S, Sambuco F, Riva E, Ciccozzi M, Angeletti S.   +12 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source