Results 11 to 20 of about 255,990 (266)

Centrin-Deleted Leishmania donovani Parasites Help CD4+ T Cells to Acquire Th1 Phenotype and Multi-Functionality Through Downregulation of CD200–CD200R Immune Inhibitory Axis

Frontiers in Immunology, 2018
The protozoan parasite Leishmania has evolved several strategies to undermine host defense mechanisms by inducing Th2-type adaptive immunity and suppressing effector functions of Th1 phenotype.
Rakesh K. Singh, Rakesh K. Singh, Sreenivas Gannavaram, Nevien Ismail, Amit Kaul, Amit Kaul, Mallikarjuna Rao Gedda, Hira L. Nakhasi   +7 more
doaj   +1 more source

Real-World Study: Hybrid Immunity against SARS-CoV-2 Influences the Antibody Levels and Persistency Lasting More than One Year

Vaccines, 2023
This study investigated the impact of hybrid immunity on antibody responses in the participants who received two to seven doses of the COVID-19 vaccine. The study was conducted between April and June 2023.
Sitthichai Kanokudom, Jira Chansaenroj, Suvichada Assawakosri, Nungruthai Suntronwong, Ritthideach Yorsaeng, Lakkhana Wongsrisang, Ratchadawan Aeemjinda, Preeyaporn Vichaiwattana, Sirapa Klinfueng, Thaksaporn Thatsanathorn, Sittisak Honsawek, Yong Poovorawan   +11 more
doaj   +1 more source

Innate immunity and vaccine [PDF]

Vaccine, 2010
Immune adjuvant is an artificial pathogen-associated molecular patterns (PAMP) for potentiating various immune responses. Vaccine represents one event that is capable of inducing immune response caused by antigen and PAMP stimuli, which act on antigen-presenting dendritic cells (mDCs).
openaire   +3 more sources

Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever

Frontiers in Immunology, 2017
The mechanisms by which oral, live-attenuated vaccines protect against typhoid fever are poorly understood. Here, we analyze transcriptional responses after vaccination with Ty21a or vaccine candidate, M01ZH09.
Christoph J. Blohmke, Jennifer Hill, Thomas C. Darton, Thomas C. Darton, Matheus Carvalho-Burger, Andrew Eustace, Claire Jones, Fernanda Schreiber, Martin R. Goodier, Gordon Dougan, Helder I. Nakaya, Andrew J. Pollard   +11 more
doaj   +1 more source

A Bovine Enteric Mycobacterium Infection Model to Analyze Parenteral Vaccine-Induced Mucosal Immunity and Accelerate Vaccine Discovery

Frontiers in Immunology, 2020
Mycobacterial diseases of cattle are responsible for considerable production losses worldwide. In addition to their importance in animals, these infections offer a nuanced approach to understanding persistent mycobacterial infection in native host ...
Antonio Facciuolo, Amy H. Lee, Amy H. Lee, Michael J. Trimble, Neil Rawlyk, Hugh G. G. Townsend, Manjeet Bains, Natasa Arsic, Lucy M. Mutharia, Andrew Potter, Volker Gerdts, Scott Napper, Scott Napper, Robert E. W. Hancock, Philip J. Griebel, Philip J. Griebel   +15 more
doaj   +1 more source

The herd-immunity threshold must be updated for multi-vaccine strategies and multiple variants

Scientific Reports, 2021
Several vaccines with different efficacies and effectivenesses are currently being distributed across the world to control the COVID-19 pandemic. Having enough doses from the most efficient vaccines in a short time is not possible for all countries ...
Iraj Yadegari, Mehdi Omidi, Stacey R. Smith   +2 more
doaj   +1 more source

Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

Vaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li, Yiwen Zhao, Yibo Li, Xinyuan Chen   +3 more
doaj   +1 more source

Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection

Frontiers in Immunology, 2020
Chronic enteric Mycobacterium avium ssp. paratuberculosis (MAP) infections are endemic in ruminants globally resulting in significant production losses. The mucosal immune responses occurring at the site of infection, specifically in Peyer's patches (PP),
Antonio Facciuolo, Amy H. Lee, Patricia Gonzalez Cano, Hugh G. G. Townsend, Reza Falsafi, Volker Gerdts, Andrew Potter, Scott Napper, Scott Napper, R. E. W. Hancock, Lucy M. Mutharia, Philip J. Griebel, Philip J. Griebel   +12 more
doaj   +1 more source

Systems Immunology: Revealing Influenza Immunological Imprint

Viruses, 2021
Understanding protective influenza immunity and identifying immune correlates of protection poses a major challenge and requires an appreciation of the immune system in all of its complexity.
Adriana Tomic, Andrew J. Pollard, Mark M. Davis   +2 more
doaj   +1 more source

High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine Recipients

Microbiology Spectrum, 2021
The prompt rollout of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine is facilitating population immunity, which is becoming more dominant than natural infection-mediated immunity.
Yuko Nitahara, Yu Nakagama, Natsuko Kaku, Katherine Candray, Yu Michimuko, Evariste Tshibangu-Kabamba, Akira Kaneko, Hiromasa Yamamoto, Yasumitsu Mizobata, Hiroshi Kakeya, Mayo Yasugi, Yasutoshi Kido   +11 more
doaj   +1 more source