Results 21 to 30 of about 255,990 (266)

Cancer and COVID-19: A review of immune insights and partnerships to inform public health strategy

International Journal of Infectious Diseases
Objective: To summarize current evidence on SARS-CoV-2 vaccine immunogenicity in cancer populations, review the experimental approaches and assays used to evaluate multilayer immunity, and highlight emerging collaborative efforts that support more ...
Heidi Hempel, Huijing Xue, Shin La Shu, Shweta Jain, Troy J. Kemp, Ligia A. Pinto   +5 more
doaj   +1 more source

Vaccine immunity

Immunology Today, 1997
A recent meeting on vaccine immunity focused on the key issue that confronts immunologists in developing a new generation of vaccines: how to initiate powerful and long-dived immune responses without stimulating excessive inflammation or autoimmunity.
openaire   +2 more sources

Measuring Humoral Immune Responses to SARS-CoV-2: A Comprehensive Review of Serological Assays

Vaccines
The COVID-19 pandemic highlighted the critical role of serological assays in understanding antiviral immune responses, monitoring vaccine efficacy, and informing public health strategies.
Huijing Xue, Katarzyna Haynesworth, Heidi A. Hempel, Troy J. Kemp, Ligia A. Pinto   +4 more
doaj   +1 more source

Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine

Human Vaccines & Immunotherapeutics, 2021
The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao, Jing Li, Hongyuan Shi, Hui Ye, Rufei Ma, Yuting Fu, Xiaochang Liu, Guoliang Li, Xiaolei Yang, Zhimei Zhao, Jingsi Yang   +10 more
doaj   +1 more source

Long-Term Cross Immune Response in Mice following Heterologous Prime-Boost COVID-19 Vaccination with Full-Length Spike mRNA and Recombinant S1 Protein

Vaccines, 2023
(1) Background: As the COVID-19 pandemic enters its fourth year, it continues to cause significant morbidity and mortality worldwide. Although various vaccines have been approved and the use of homologous or heterologous boost doses is widely promoted ...
Dandan Li, Heng Zhao, Yun Liao, Guorun Jiang, Pingfang Cui, Ying Zhang, Li Yu, Shengtao Fan, Hangwen Li, Qihan Li   +9 more
doaj   +1 more source

Reproducibility Assessment of Enzyme-Linked Immunosorbent Assays to Detect Anti-HPV16 L1-Specific IgG1, IgG3, IgA, and IgM Antibodies

Vaccines
Background/Objectives: Enzyme-linked immunosorbent assays (ELISAs) have been used to measure anti-human-papillomavirus (HPV) immunoglobulin IgG. The goal of this study was to evaluate the reproducibility of ELISAs measuring different HPV immunoglobulin ...
Ken Matsui, Heidi Anne Hempel, Gloriana Shelton, Rebecca Ocampo, Troy J. Kemp, Yuanji Pan, Ligia A. Pinto   +6 more
doaj   +1 more source

Vaccines and Principles of Immunization

Veterinary Clinics of North America: Small Animal Practice, 1986
This article discusses the production of the various classes of vaccines and compares the advantages and disadvantages of each. Adjuvants, combination vaccines, heterologous viral vaccines, and vaccination failure are discussed briefly. Reported adverse reactions to vaccination are described at length.
Pearson, Renée C., Dhein, Cheryl R., Gorham, John R.   +2 more
openaire   +2 more sources

Analytical measuring interval, linearity, and precision of serology assays for detection of SARS-CoV-2 antibodies according to CLSI guidelines

mSphere
Serology testing is commonly used to evaluate the immunogenicity of COVID-19 vaccines and measure antibodies as a marker of previous infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Katarzyna Haynesworth, Troy J. Kemp, Sarah A Loftus, Jordan Metz, Nicholas C. Castro, Jimmie Bullock, David Fetterer, Ligia A. Pinto   +7 more
doaj   +1 more source

Near-Complete SARS-CoV-2 Seroprevalence among Rural and Urban Kenyans despite Significant Vaccine Hesitancy and Refusal

Vaccines, 2022
Considering the early inequity in global COVID-19 vaccine distribution, we compared the level of population immunity to SARS-CoV-2 with vaccine uptake and refusal between rural and urban Kenya two years after the pandemic onset.
Carolyne Nasimiyu, Isaac Ngere, Jeanette Dawa, Patrick Amoth, Ouma Oluga, Carol Ngunu, Harriet Mirieri, John Gachohi, Moshe Dayan, Nzisa Liku, Ruth Njoroge, Raymond Odinoh, Samuel Owaka, Samoel A. Khamadi, Samson L. Konongoi, Sudi Galo, Linet Elamenya, Marianne Mureithi, Omu Anzala, Robert Breiman, Eric Osoro, M. Kariuki Njenga   +21 more
doaj   +1 more source

Longitudinal Assessment of BNT162b2- and mRNA-1273-Induced Anti-SARS-CoV-2 Spike IgG Levels and Avidity Following Three Doses of Vaccination

Vaccines
SARS-CoV-2 vaccination-induced protection against infection is likely to be affected by functional antibody features. To understand the kinetics of antibody responses in healthy individuals after primary series and third vaccine doses, sera from the ...
Jimmie L. Bullock, Thomas E. Hickey, Troy J. Kemp, Jordan Metz, Sarah Loftus, Katarzyna Haynesworth, Nicholas Castro, Brian T. Luke, Douglas R. Lowy, Ligia A. Pinto   +9 more
doaj   +1 more source