Results 141 to 150 of about 1,499,954 (350)
A live attenuated varicella vaccine
The vaccine virus was isolated from a vesicle of a 3-year-old otherwise healthy boy called Oka (his family name) who had typical varicella. This virus was passaged through human embryonic lung cells, guinea pig embryonic cells at a low temperature, and human diploid cells (WI-38). It was then adapted to MRC-5 human diploid cells for vaccine preparation.
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Live Attenuated Mumps Virus Vaccine. 1. Vaccine Development
SummaryThe development and testing of an attenuated live mumps virus vaccine designated Jeryl Lynn strain, level B, is described.
E B, Buynak, M R, Hilleman
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Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
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ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
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Development and Application of Attenuated Plant Viruses as Biological Control Agents in Japan
In 1929, it was reported that yellowing symptoms caused by a tobacco mosaic virus (TMV) yellow mosaic isolate were suppressed in tobacco plants that were systemically infected with a TMV light green isolate.
Yasuhiro Tomitaka +6 more
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The landscape of infant bronchiolitis and viral pneumonia may be altered by preventive interventions against respiratory syncytial virus under evaluation today.
Sofia S. Aranda, Fernando P. Polack
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Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
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Citation: 'attenuated vaccine' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12911 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
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The success of the two rotavirus (RV) vaccines (Rotarix and RotaTeq) in many countries endorses a live attenuated vaccine approach against RVs. However, the lower efficacies of both vaccines in many low- and middle-income countries indicate a need to ...
Xi Jiang, Yang Liu, Ming Tan
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