Results 181 to 190 of about 123,822 (310)

Safety, immunogenicity, and effectiveness of the MAV/06 varicella vaccine: A comprehensive review of a new strain vaccine. [PDF]

Hum Vaccin Immunother
Shin Y, Ryu H, Kim G, Yang S, Lee J, Choi B.   +5 more
europepmc   +1 more source

Attenuated Live Vaccine [PDF]

, 2020
openaire   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Serial Cell-Culture Passage of Severe Fever with Thrombocytopenia Syndrome Virus Attenuates Virulence and Confers Protective Immunity in Mice. [PDF]

Viruses
Kim J, Kim YE, Kang HJ, Ryou J, Chu H, Yun SM.   +5 more
europepmc   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

iNew Medicine, EarlyView.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu, Zhicheng Yu, Yang Zhang, Hui Hong, Xiaoli Wang, Shan Jiang, Ying Zhou, Cheng Peng, Hongbo Chen   +8 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Parental preference for live-attenuated versus inactivated influenza vaccination in children: A questionnaire survey. [PDF]

Hum Vaccin Immunother
Kitano T, Kurosawa N, Hirano S, Okamura T, Hachisuka S, Yamamoto N, Nishikawa H, Onaka M, Suzuki R, Yoshida S.   +9 more
europepmc   +1 more source

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage [PDF]

, 2017
Diamond, Michael S, et al,, Jagger, Brett W, Richner, Justin   +3 more
core   +2 more sources

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Recent Advances, Bottlenecks, and Future Directions in <i>Plasmodium falciparum</i> Vaccine Development. [PDF]

Vaccines (Basel)
Turan G, Boggio MJ, Othman AS, Nnaemeka V, Hill AVS, Salman AM.   +5 more
europepmc   +1 more source