Results 11 to 20 of about 68,108 (241)
Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines
Frontiers in Veterinary Science, 2021 The success of inactivated and live-attenuated vaccines has enhanced livestock productivity, promoted food security, and attenuated the morbidity and mortality of several human, animal, and zoonotic diseases.
Virginia Aida +14 more
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Frontiers in Microbiology, 2023 Since its outbreak in 2010, Tembusu virus (TMUV) has spread widely throughout China and Southeast Asia, causing significant economic losses to the poultry industry.
Bangfeng Xu +7 more
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Attenuated Vaccines for Augmented Immunity [PDF]
Cell Host & Microbe, 2017 Live attenuated vaccines are more immunogenic and have the capacity to elicit long-lasting immune responses. In two recent studies, Wang et al. (2017) and Si et al. (2016) describe strategies for the generation of live attenuated influenza viruses, which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.
Jeffrey V. Ravetch, Stylianos Bournazos
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LIVE ATTENUATED VACCINES FOR THE IMMUNOPROPHYLAXIS
Инфекция и иммунитет, 2017 The review focuses on the history of the production of live antiviral vaccines and their use for the prevention of infectious diseases. It was noted that before the beginning of the 20th century, only three live vaccines were developed and put into ...
O. A. Shamsutdinova
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Virulence, 2022 One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu +5 more
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Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives
Frontiers in Immunology, 2021 BackgroundCurrent vaccination strategies against pertussis are sub-optimal. Optimal protection against Bordetella pertussis, the causative agent of pertussis, likely requires mucosal immunity.
Violaine Dubois, Camille Locht
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LC16m8: An attenuated smallpox vaccine
Vaccine, 2006 The frequency of moderate to severe adverse reactions associated with smallpox vaccines currently stockpiled in the US, and the continued threat of bioterrorism have prompted the development of effective vaccines with improved safety profiles. LC16m8, an attenuated, replicating smallpox vaccine derived from the Lister strain of vaccinia, is currently ...
Marc Gurwith +4 more
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New Points of Departure for More Global Influenza Vaccine Use
Vaccines, 2020 Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to year.
Irina Kiseleva
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Live attenuated intranasal influenza vaccine [PDF]
Human Vaccines & Immunotherapeutics, 2012 Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
Esposito, Susanna Maria Roberta +5 more
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Directed attenuation to enhance vaccine immunity
PLOS Computational Biology, 2021 Many viral infections can be prevented by immunizing with live, attenuated vaccines. Early methods of attenuation were hit-and-miss, now much improved by genetic engineering. However, even current methods operate on the principle of genetic harm, reducing the virus’s ability to grow.
Rustom Antia, Hasan Ahmed, James J. Bull
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