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MicroRNA-Attenuated Virus Vaccines [PDF]
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
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Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines [PDF]
Emergent coronaviruses remain a significant threat to global public health and rapid response vaccine platforms are needed to stem future outbreaks.
Vineet D. Menachery +9 more
semanticscholar +3 more sources
Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis”
The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan +6 more
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An overview on inactivated and live‐attenuated SARS‐CoV‐2 vaccines
After about 2 years since severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), first infections were detected in Wuhan city of China in December 2019, which was followed by a worldwide pandemic with a record of 5.41 million deaths. Due to urgent
S. Khoshnood +7 more
semanticscholar +1 more source
Vaccination is an effective approach to prevent, control and eradicate diseases, including lumpy skin disease (LSD). One of the measures to address farmer hesitation to vaccinate is guaranteeing the quality of vaccine batches.
A. Haegeman +8 more
semanticscholar +1 more source
Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use
Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur +4 more
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Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses
Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield +3 more
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Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines
The success of inactivated and live-attenuated vaccines has enhanced livestock productivity, promoted food security, and attenuated the morbidity and mortality of several human, animal, and zoonotic diseases.
Virginia Aida +14 more
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Cold adapted live attenuated influenza vaccines can effectively prevent human disease and death caused by influenza virus. Since chicken embryos are used as the culture substrate for the large-scale production of influenza vaccines, cold adapted live ...
Min Wu +14 more
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Overview of the Development, Impacts, and Challenges of Live-Attenuated Oral Rotavirus Vaccines
Safety, efficacy, and cost-effectiveness are paramount to vaccine development. Following the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe dehydrating diarrhoea in infants and young children worldwide, the quest to ...
Olufemi S. Folorunso, O. Sebolai
semanticscholar +1 more source

