Results 21 to 30 of about 122,871 (313)

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus [PDF]

open access: yes, 2014
Bluetongue is one of the major infectious diseases of ruminants and is caused by Bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV.
Brunet, Silvie   +6 more
core   +2 more sources

Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges

open access: yesBMC Veterinary Research, 2012
Background The porcine reproductive and respiratory syndrome virus (PRRSV) is a rapidly evolving pathogen of swine. At present, there is a high demand for safe and more effective vaccines that can be adapted regularly to emerging virus variants. A recent
Geldhof Marc F   +5 more
doaj   +1 more source

Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum

open access: yesPoultry Science, 2020
Mycoplasma gallisepticum (MG) is an important avian pathogen that causes significant economic losses in the poultry industry. Surprisingly, the limited protection and adverse reactions caused by the vaccines, including live vaccines, bacterin-based ...
Muhammad Ishfaq   +5 more
doaj   +1 more source

Blood B Cell Depletion Reflects Immunosuppression Induced by Live-Attenuated Infectious Bursal Disease Vaccines

open access: yesFrontiers in Veterinary Science, 2022
Immunosuppression in poultry production is a recurrent problem worldwide, and one of the major viral immunosuppressive agents is Infectious Bursal Disease Virus (IBDV). IBDV infections are mostly controlled by using live-attenuated vaccines.
Céline Courtillon   +8 more
doaj   +1 more source

Identification of an essential virulence gene of cyprinid herpesvirus 3 [PDF]

open access: yes, 2017
The genus Cyprinivirus consists of a growing list of phylogenetically related viruses, some of which cause severe economic losses to the aquaculture industry. The archetypal member, cyprinid herpesvirus 3 (CyHV-3) causes mass mortalities worldwide in koi
Boutier, Maxime   +5 more
core   +2 more sources

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

open access: yes, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR   +8 more
core   +1 more source

EXPERIMENTAL MEASLES VACCINES: A RESEARCH TOOL IN VACCINATION EVENTS

open access: yesМедицинская иммунология, 2014
. The review article considers different variants of measles vaccine that may be classified into two groups, i.e., vaccines that do not contain viable measles virus, and attenuated measles vaccines which could be employed in unusual manner.The first ...
V. A. Liashenko
doaj   +1 more source

Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives

open access: yesFrontiers in Immunology, 2021
BackgroundCurrent vaccination strategies against pertussis are sub-optimal. Optimal protection against Bordetella pertussis, the causative agent of pertussis, likely requires mucosal immunity.
Violaine Dubois, Camille Locht
doaj   +1 more source

Roadblocks to translational challenges on viral pathogenesis. [PDF]

open access: yes, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven   +4 more
core   +1 more source

Live Attenuated Varicella Vaccine

open access: yesThe Journal of Pediatrics, 1984
Live attenuated varicella vaccine will in all probability soon be licensed in the United States for immunization of healthy children and adults and certain immunocompromised children. This vaccine can be expected to protect susceptibles from varicella (or to modify it) in those subsequently exposed to the wild virus.
openaire   +6 more sources

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