Results 21 to 30 of about 1,439,979 (204)
Overview of the Development, Impacts, and Challenges of Live-Attenuated Oral Rotavirus Vaccines
Vaccines, 2020 Safety, efficacy, and cost-effectiveness are paramount to vaccine development. Following the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe dehydrating diarrhoea in infants and young children worldwide, the quest to ...
Olufemi S. Folorunso, O. Sebolai
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The Effects of Pre-Existing Antibodies on Live-Attenuated Viral Vaccines
Viruses, 2020 Live-attenuated vaccines (LAVs) have achieved remarkable successes in controlling virus spread, as well as for other applications such as cancer immunotherapy.
Darren Z L Mok, Kuan Rong Chan
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Live Attenuated Cold-Adapted Influenza Vaccines.
Cold Spring Harbor Perspectives in Medicine, 2020 Live attenuated, cold-adapted influenza vaccines exhibit several desirable characteristics, including the induction of systemic, mucosal, and cell-mediated immunity resulting in breadth of protection, ease of administration, and yield.
K. Subbarao
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Next-Generation TB Vaccines: Progress, Challenges, and Prospects
Vaccines, 2023 Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global infectious disease and a leading cause of mortality worldwide. Currently, the only available vaccine for TB prevention is Bacillus Calmette–Guérin (BCG).
Zhuang Li +4 more
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Attenuated Vaccines for Augmented Immunity [PDF]
Cell Host & Microbe, 2017 Live attenuated vaccines are more immunogenic and have the capacity to elicit long-lasting immune responses. In two recent studies, Wang et al. (2017) and Si et al. (2016) describe strategies for the generation of live attenuated influenza viruses, which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.
Stylianos, Bournazos, Jeffrey V, Ravetch
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Respiratory Syncytial Virus Vaccines: A Review of the Candidates and the Approved Vaccines
Pathogens, 2023 Respiratory syncytial virus (RSV) is responsible for a significant proportion of global morbidity and mortality affecting young children and older adults.
Xanthippi Topalidou +2 more
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Frontiers in Microbiology, 2023 Since its outbreak in 2010, Tembusu virus (TMUV) has spread widely throughout China and Southeast Asia, causing significant economic losses to the poultry industry.
Bangfeng Xu +7 more
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Vaccines, 2023 The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR) bacteria, leading to the current antibiotic resistance crisis. To address this issue, next-generation vaccines are being developed to prevent antimicrobial resistance ...
Kanwal Khalid, C. Poh
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LIVE ATTENUATED VACCINES FOR THE IMMUNOPROPHYLAXIS
Инфекция и иммунитет, 2017 The review focuses on the history of the production of live antiviral vaccines and their use for the prevention of infectious diseases. It was noted that before the beginning of the 20th century, only three live vaccines were developed and put into ...
O. A. Shamsutdinova
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Virulence, 2022 One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu +5 more
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