Results 41 to 50 of about 1,439,979 (204)

Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists

Vaccines, 2016
The interferon (IFN) induced anti-viral response is amongst the earliest and most potent of the innate responses to fight viral infection. The induction of the Janus kinase/signal transducer and activation of transcription (JAK/STAT) signalling pathway ...
S. Fleming
semanticscholar   +1 more source

A review on the recent advances and application of vaccines against fish pathogens in aquaculture

Aquaculture International, 2022
Globally, aquaculture has faced serious economic problems due to bacterial, viral, and various other infectious diseases of different origins. Even though such diseases are being detected and simultaneously treated with several therapeutic and ...
Haimanti Mondal, John Thomas
semanticscholar   +1 more source

EXPERIMENTAL MEASLES VACCINES: A RESEARCH TOOL IN VACCINATION EVENTS

Медицинская иммунология, 2014
. The review article considers different variants of measles vaccine that may be classified into two groups, i.e., vaccines that do not contain viable measles virus, and attenuated measles vaccines which could be employed in unusual manner.The first ...
V. A. Liashenko
doaj   +1 more source

Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus.

JCI Insight, 2017
Chikungunya virus (CHIKV) is rapidly spreading across the globe, and millions are infected. Morbidity due to this virus is a serious threat to public health, but at present, there is no vaccine against this debilitating disease.
P. Roques, K. Ljungberg, B. Kümmerer, L. Gosse, N. Dereuddre-Bosquet, N. Tchitchek, D. Hallengärd, J. García-Arriaza, A. Meinke, M. Esteban, A. Merits, R. Le Grand, P. Liljeström   +12 more
semanticscholar   +1 more source

Influenza Viruses and Vaccines: The Role of Vaccine Effectiveness Studies for Evaluation of the Benefits of Influenza Vaccines

Vaccines, 2022
Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
C. Trombetta, O. Kistner, E. Montomoli, S. Viviani, S. Marchi   +4 more
semanticscholar   +1 more source

Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives

Frontiers in Immunology, 2021
BackgroundCurrent vaccination strategies against pertussis are sub-optimal. Optimal protection against Bordetella pertussis, the causative agent of pertussis, likely requires mucosal immunity.
Violaine Dubois, Camille Locht
doaj   +1 more source

Live Attenuated Varicella Vaccine

The Journal of Pediatrics, 1985
Live attenuated varicella vaccine will in all probability soon be licensed in the United States for immunization of healthy children and adults and certain immunocompromised children. This vaccine can be expected to protect susceptibles from varicella (or to modify it) in those subsequently exposed to the wild virus.
openaire   +6 more sources

Recent progress on gene-deleted live-attenuated African swine fever virus vaccines

npj Vaccines
African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security ...
Hiep L. X. Vu, D. S. McVey
semanticscholar   +1 more source

Preventing the Next Pandemic: Is Live Vaccine Efficacious against Monkeypox, or Is There a Need for Killed Virus and mRNA Vaccines?

Vaccines, 2022
(1) Background: The monkeypox virus (MPV) is a double-stranded DNA virus belonging to the Poxviridae family, Chordopoxvirinae subfamily, and Orthopoxvirus genus.
A. Abdelaal, A. Reda, B. Lashin, B. Katamesh, A. Brakat, Balqees Al-Manaseer, Sayanika Kaur, Ankush Asija, Nimesh K. Patel, S. Basnyat, A. Rabaan, S. Alhumaid, Hawra Albayat, M. Aljeldah, B. A. Shammari, A. Al-Najjar, Ahmed K. Al-Jassem, Sultan T AlShurbaji, F. Alshahrani, Ahlam Alynbiawi, Zainab H. Alfaraj, Duaa H. Alfaraj, Ahmed H. Aldawood, Y. Sedhai, Victoria Mumbo, A. Rodríguez-Morales, R. Sah   +26 more
semanticscholar   +1 more source

Developing live vaccines against plague

Journal of Infection in Developing Countries, 2011
Three great plague pandemics caused by the gram-negative bacterium Yersinia pestis have killed nearly 200 million people and it has been linked to biowarfare in the past. Plague is endemic in many parts of the world.
Wei Sun, Kenneth L Roland, Roy Curtiss III   +2 more
doaj   +1 more source