Results 161 to 170 of about 1,023,792 (288)

Conjugate-like immunogens produced as protein capsular matrix vaccines

Proceedings of the National Academy of Sciences of the United States of America, 2015
A. Thanawastien, R. Cartee, Thomas J Griffin, K. Killeen, J. Mekalanos   +4 more
semanticscholar   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source

Cost-effectiveness analysis of routine pediatric vaccination of 15-valent pneumococcal conjugate vaccine in South Korea. [PDF]

Hum Vaccin Immunother
Choe YJ, Jeon Y, Park J, Kim H, Yang G, Mohanty S, Floros L, Huang M, Chhabra N, Kumari S, Singh J, Sukarom I.   +11 more
europepmc   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

An Evaluation of the Safety, Immunogenicity, and Protective Efficacy of a Combined Diphtheria-Tetanus-Acellular Pertussis, <i>Haemophilus influenzae</i> Type b, and ACYW135 Meningococcal Conjugate Vaccine in Murine and Rat Models. [PDF]

Vaccines (Basel)
Sui X, Shao Z, Ji Y, Wang H, Xu Q, Wei B, Duan Z, Wang C, Yang Y, Zhao J, Zhu T.   +10 more
europepmc   +1 more source

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

Advanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani, Lauren Dawson, Haley Flowers, Kathleen L. Vincent, Samuel K. Lai   +8 more
wiley   +1 more source

Conjugate Vaccines for Streptococcus pneumoniae

Canadian Journal of Infectious Diseases, 1999
Peter R Paradiso
doaj   +1 more source

The New Era of Pneumococcal Vaccination in Adults: What Is Next? [PDF]

Vaccines (Basel)
Ozisik L.
europepmc   +1 more source

Rapid‐Turnaround Co‐Administration of mRNA‐Based MHC‐I and MHC‐II‐Restricted Neoantigens Enhances Immune Responses of Antigen‐Specific CD8+ T Cells and Anti‐Cancer Efficacy in Colorectal Cancer

Advanced Science, EarlyView.
Co‐administration with MHC class I‐ and II‐restricted neoantigens encoding mRNA‐based personalized cancer vaccines in a mouse CRC model can induce antigen‐specific immune responses and anti‐cancer effects. Notably, vaccination at an early stage of cancer development can have potent anti‐cancer effects. Furthermore, combining mRNA with immune checkpoint
Seongje Cho, Woori Kwak, Hyunho Yoon, Jisun Lee, Seonghyun Lee, Hyo‐Jung Park, Sohee Jo, Yu‐Sun Lee, Yu‐Jeong Seo, Youngran Cho, Seo‐Hyeon Bae, Subin Yoon, Gahyun Roh, Dahyeon Ha, Ayoung Oh, Eun‐Jin Choi, Soo‐Yeon Lee, Huijeong Choi, Jungmin Kim, Yeeun Lee, Sowon Lee, Sang‐In Park, Dae‐Keun Kim, Jun Chang, Ki Tae Kim, Kwoneel Kim, Jae‐Hwan Nam   +26 more
wiley   +1 more source

Novel synthetic peptide-based vaccine shows promise against prostate cancer. [PDF]

Mol Ther Oncol
Vázquez-Arreguín K.
europepmc   +1 more source