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Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. [PDF]
, 2018 Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Although this is a vaccine preventable disease, S. pneumoniae still causes over 1 million deaths per year, mainly in children under the age of five.
Abouelhadid, Sherif +7 more
core +3 more sources
Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples. [PDF]
, 2014 Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current ...
Adegbola, Richard A +20 more
core +1 more source
Journal of Epidemiology and Global Health, 2019 Facing the availability of the new generation of quadrivalent meningococcal conjugate vaccines (Menveo®, Menactra® and others pending for license) and their recent implementation in Saudi Arabia, experts from 11 countries of the Middle East region met at
Atef Shibl +4 more
doaj +1 more source
Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis [PDF]
, 2014 Staphylococcus aureus is an invasive bacterial pathogen, and antibiotic resistance has impeded adequate control of infections caused by this microbe. Moreover, efforts to prevent human infections with single-component S. aureus vaccines have failed.
Buzzola, Fernanda Roxana +6 more
core +2 more sources
Nature Biotechnology, 2019 Personalized cancer vaccines targeting patient-specific neoantigens are a promising cancer treatment modality; however, neoantigen physicochemical variability can present challenges to manufacturing personalized cancer vaccines in an optimal format for ...
G. Lynn +29 more
semanticscholar +1 more source
Promising directions for vaccine development to prevent shigellosis
Биопрепараты: Профилактика, диагностика, лечение, 2022 Shigellosis (bacterial dysentery) is an acute infectious disease caused by Shigella spp., members of the Enterobacteriaceae family. The disease has the highest mortality rate amongst bacterial enteric infections.
M. V. Abramtseva +2 more
doaj +1 more source
Adesão às novas vacinas conjugadas. Vacina anti-meningocócica e anti-pneumocócica.
Acta Médica Portuguesa, 2004 The new conjugate vaccines against group C meningococcal infection and pneumococcal infection were introduced in Portugal in 2001. In 2001/2002, the media published several alarming news on meningococcal disease and there was an increased demand of those
Laurinda De Queirós +3 more
doaj +1 more source
Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
, 2012 SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source
Human Vaccines & Immunotherapeutics, 2019 Invasive meningococcal disease is rare and potentially devastating but often vaccine-preventable. Evaluation of meningococcal vaccine effectiveness is impractical owing to relatively low disease incidence; protection is therefore estimated using serum ...
J. Findlow, P. Balmer, R. Borrow
semanticscholar +1 more source
Expert Review of Vaccines, 2019 Introduction: Streptococcus pneumoniae is a leading cause of morbidity and mortality worldwide. Widespread infant vaccination with pneumococcal conjugate vaccines (PCVs) substantially reduced vaccine-serotype pneumococcal disease by direct protection of ...
R. Dagan
semanticscholar +1 more source