Results 21 to 30 of about 16,296 (221)
ERA OF CONJUGATE VACCINES: INTERNATIONAL EXPERIENCE OF SUCCESSFUL APPLICATION
The article highlights comparative characteristics of the polysaccharide and conjugate vaccines against pneumococcal infection, meningococcosis and haemophilus influenza. The author stresses the advantage of the conjugate vaccines.
M.V. Fedoseenko+2 more
doaj +2 more sources
Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk of ...
Olivia K Burn+15 more
doaj +1 more source
The Impact of Vaccination Behavior on Disease Spreading Based on Complex Networks [PDF]
Vaccination is an effective way to prevent and control the occurrence and epidemic of infectious diseases. However, many factors influence whether the residents decide to get vaccinated or not, such as the efficacy and side effects while individuals hope to obtain immunity through vaccination.
arxiv
Simultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into ...
Paolo Bonanni+6 more
doaj +1 more source
COVID-19 Vaccine Hesitancy and Information Diffusion: An Agent-based Modeling Approach [PDF]
Despite the unprecedented success in the rapid development of several effective vaccines against the Cov-SARS-2, global vaccination rollout efforts suffer from vaccine distribution inequality and vaccine acceptance, leading to insufficient public immunity provided by the vaccine products.
arxiv
Histo-blood group glycans in the context of personalized medicine [PDF]
Background: A subset of histo-blood group antigens including ABO and Lewis are oligosaccharide structures which may be conjugated to lipids or proteins. They are known to be important recognition motifs not only in the context of blood transfusions, but also in infection and cancer development.
arxiv +1 more source
Conjugate vaccines in which the capsular polysaccharide of Haemophilus influenzae type b, common serotypes of Streptococcus pneumoniae and group C Neisseria meningitidis are covalently bound to a protein antigen to convert a T-cell-independent immune response into a T-cell-dependent response have proved highly effective in the prevention of invasive ...
openaire +2 more sources
Development of a novel glycoengineering platform for the rapid production of conjugate vaccines
Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases.
Sherif Abouelhadid+15 more
doaj +1 more source
Evolution of conjugate vaccines
Conjugate vaccines--bacterial polysaccharides conjugated to proteins to improve their immunizing properties--have been a success story since their introduction less than 20 years ago. The Haemophilus influenzae type b conjugate vaccine has nearly eliminated invasive Haemophilus influenzae type b disease in large parts of the world.
P. Helena Mäkelä, Helena Käyhty
openaire +3 more sources
Conjugate vaccines have reduced the incidence of invasive disease caused by Haemophilus influenzae, type b (Hib), in industrialized countries and may be highly effective against Streptococcus pneumoniae.
Marc Lipsitch
doaj +1 more source