Results 41 to 50 of about 1,085,685 (349)

Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis [PDF]

open access: yes, 2014
Staphylococcus aureus is an invasive bacterial pathogen, and antibiotic resistance has impeded adequate control of infections caused by this microbe. Moreover, efforts to prevent human infections with single-component S. aureus vaccines have failed.
Buzzola, Fernanda Roxana   +6 more
core   +2 more sources

Conjugate vaccines

open access: yesExpert Review of Vaccines, 2003
Conjugate vaccines in which the capsular polysaccharide of Haemophilus influenzae type b, common serotypes of Streptococcus pneumoniae and group C Neisseria meningitidis are covalently bound to a protein antigen to convert a T-cell-independent immune response into a T-cell-dependent response have proved highly effective in the prevention of invasive ...
openaire   +2 more sources

Extensively Drug-Resistant Typhoid - Are Conjugate Vaccines Arriving Just in Time?

open access: yesNew England Journal of Medicine, 2018
Extensively Drug-Resistant Typhoid More than 1000 cases of XDR Salmonella Typhi have been confirmed in Pakistan. Until recently, vaccines against typhoid have had limited efficacy and durability of immunogenicity, but an effective conjugate vaccine is ...
J. Andrews   +3 more
semanticscholar   +1 more source

Production of glycoprotein vaccines in Escherichia coli

open access: yesMicrobial Cell Factories, 2010
Background Conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens.
Ihssen Julian   +5 more
doaj   +1 more source

Comparison of Strategies and Incidence Thresholds for Vi Conjugate Vaccines Against Typhoid Fever: A Cost-effectiveness Modeling Study

open access: yesJournal of Infectious Diseases, 2018
Background Typhoid fever remains a major public health problem globally. While new Vi conjugate vaccines hold promise for averting disease, the optimal programmatic delivery remains unclear.
N. Lo   +6 more
semanticscholar   +1 more source

Immunogenicity and safety of MenACWY-TT, a quadrivalent meningococcal tetanus toxoid conjugate vaccine recently licensed in the United States for individuals ≥2 years of age

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Vaccination offers the best way to prevent invasive meningococcal disease (IMD). As demonstrated in countries with national immunization programs (NIPs) against IMD, meningococcal conjugate vaccines have contributed to significant declines in incidence ...
Gary S. Marshall   +3 more
doaj   +1 more source

Conjugate vaccines for enteric fever: proceedings of a meeting organized in New Delhi, India in 2009

open access: yesJournal of Infection in Developing Countries, 2010
Enteric fever is responsible for significant morbidity in South Asia and high prevalence of severe disease is seen in children under two years of age. Effective typhoid vaccines are available, but they cannot be used for children under two years of age
Audino Podda   +14 more
doaj   +1 more source

Risk of transmitting meningococcal infection by transient contact on aircraft and other transport. [PDF]

open access: yes, 2009
Contact tracing of persons with meningococcal disease who have travelled on aeroplane or other multi-passenger transport is not consistent between countries.
Hellenbrand, W   +4 more
core   +3 more sources

Design and production of conjugate vaccines against S. Paratyphi A using an O-linked glycosylation system in vivo

open access: yesnpj Vaccines, 2018
Enteric fever, mainly caused by Salmonella enterica serovar Paratyphi A, remains a common and serious infectious disease worldwide. As yet, there are no licensed vaccines against S. Paratyphi A.
Peng Sun   +11 more
semanticscholar   +1 more source

Glycolipid‐peptide conjugate vaccines elicit CD8+ T‐cell responses and prevent breast cancer metastasis

open access: yesClinical & Translational Immunology, 2022
Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk of ...
Olivia K Burn   +15 more
doaj   +1 more source

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