Results 61 to 70 of about 16,296 (221)

Biocompatibility of Water‐Dispersible Pristine Graphene and Graphene Oxide Using a Close‐to‐Human Animal Model: A Pilot Study on Swine

open access: yesAdvanced Healthcare Materials, EarlyView.
Graphene‐based materials are attracting considerable interest for biomedical applications. Analysis of their biocompatibility is required before their clinical translation, and swine represents an excellent close‐to‐human model. This study evaluates the toxicological and immunological impact of pristine graphene and graphene oxide through a compendium ...
Paola Nicolussi   +26 more
wiley   +1 more source

Nueva generación de Vacunas Conjugadas Antimeningococica: Fundamentos y Posibilidades a escala Mundial

open access: yesVacciMonitor, 2009
The serogroup distribution of Neisseria meningitidis strains implicated in invasive disease varies geographically and temporally. Monovalent serogroup C conjugate vaccines have successfully reduced serogroup C disease in countries where they are used ...
Jacqueline Miller   +2 more
doaj  

The Information Ecosystem of Online Groups with Anti- and Pro-vaccine Views on Facebook [PDF]

open access: yesarXiv, 2021
Opposition and hesitancy to vaccination have been one of the major threats to global health. Social media sites have been suspected as a breeding ground of misleading narratives about vaccines, but little is known about how pervasive anti-vaccine views are on the world's largest social media, Facebook.
arxiv  

Rational Design of Conjugate Vaccines [PDF]

open access: yesPediatric Research, 1992
Whereas bacterial polysaccharides, classified as T-cell-independent antigens, elicit protective antibodies in adults, booster injections fail to produce an augmented response or promote antibody class switching. Because T-cell-dependent antigens, typically proteins, both produce boosted antibody levels and promote antibody class switching, it has been ...
openaire   +2 more sources

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

open access: yesAdvanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma   +10 more
wiley   +1 more source

Meningococcal conjugate vaccines: optimizing global impact

open access: yesInfection and Drug Resistance, 2011
Andrew Terranella1,2, Amanda Cohn2, Thomas Clark2 1Epidemic Intelligence Service, Division of Applied Sciences, Scientific Education and Professional Development Program Office, 2Meningitis and Vaccine Preventable Diseases Branch, National Center for ...
Terranella A, Cohn A, Clark T
doaj  

Vaccination dilemma on an evolving social network [PDF]

open access: yesarXiv, 2019
Vaccination is crucial for the control of epidemics. Yet it is a social dilemma since non-vaccinators can benefit from the herd immunity created by the vaccinators. Thus the optimum vaccination level is not reached via voluntary vaccination at times.
arxiv  

Vaccination strategies and transmission of COVID-19: evidence across advanced countries [PDF]

open access: yesarXiv, 2021
Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate effects on COVID-19 cases and deaths of two key elements of mass vaccination - time between doses and vaccine type.
arxiv  

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Epidemiology and Control of Meningococcal Disease in Canada: A Long, Complex, and Unfinished Story

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2019
The epidemiology of meningococcal disease in Canada has been punctuated by outbreaks caused by serogroup A strains in the 1940s, virulent serogroup C clones from 1985 to 2001, a serogroup B clone in Quebec from 2003 to 2014, and more recently a W clone ...
Philippe De Wals
doaj   +1 more source

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