ABSTRACT The 2025 Cure Ocular Melanoma (CURE OM) Global Science Meeting took place in Amsterdam, The Netherlands on October 25th, 2025. Several promising drug candidates are in development; however, there is still an urgent need for better prevention, detection, and treatment of uveal melanoma.
Andrew E. Aplin +18 more
wiley +1 more source
Plant-Based Strategies for Vaccine Development: A Narrative Review of Recombinant Biofactories, Phytochemical Adjuvants, Innovative Delivery Systems, and Insights on Oral and Edible Vaccines. [PDF]
Najafi K +3 more
europepmc +1 more source
ABSTRACT Viruses activate host defences by alerting interferon and other alarms. Viruses seeking latency must curtail this. Infected subjects would then have minimal immune system activation and remain healthy. However, a minority cannot prevent emergence of associated diseases.
Donald R. Forsdyke
wiley +1 more source
Structural studies promote vaccine development: lessons from African swine fever virus. [PDF]
Zhang Y, Zhu L.
europepmc +1 more source
Here, we introduce a biological, self‐assembling supramolecular nanoparticle designed to encapsulate eukaryotic‐expressible mRNA within an encapsulin shell via an encapsulin‐RNA adaptor peptide (ERAP). This process occurs in bacteria, and the resulting complex can deliver its mRNA into eukaryotic cells, where it is expressed.
Carlos Francisco Coffeen +5 more
wiley +1 more source
Brucellosis vaccine development: immunological mechanisms, animal models, and future directions. [PDF]
Zhang Y +5 more
europepmc +1 more source
Immunopotentiation by Natural Extracts: Mechanisms and Applications in Influenza Vaccine Adjuvant Development. [PDF]
Ho TL, Ko EJ.
europepmc +1 more source
A Rabies Virus Glycoprotein Subunit Vaccine Produced in <i>Pichia pastoris</i> Induces Neutralizing Antibodies in Mice. [PDF]
Yang Y +11 more
europepmc +1 more source
A Modular Design of a Cholera Toxin B Subunit-Scaffolded Sub-Virion Nanoparticle Vaccine Against West Nile Virus. [PDF]
Byun H +13 more
europepmc +1 more source
Advances and Translational Challenges in <i>Toxoplasma gondii</i> Vaccine Development: From Antigen Discovery to mRNA and One Health Strategies. [PDF]
Qadeer A +4 more
europepmc +1 more source

