Results 211 to 220 of about 1,792,624 (390)

Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged 65 and Over in England and Wales

, 2018
Abdelmajid Djennad, Mary Ramsay, Richard Pebody, Norman K. Fry, Carmen Sheppard, Shamez Ladhani, Nick Andrews   +6 more
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Long-Term Impacts of Invasive Meningococcal Disease on Survivors and Their Caregivers in the United States and Canada

Infectious Diseases and Therapy
Introduction Adolescents and young adults are among those most often impacted by invasive meningococcal disease (IMD), and survivors are often left with serious and permanent physical, neurological, psychological, or systemic complications.
Todd Wolynn, John B. Grimes, Sayali Nerurkar, Rachel Dawson, Katherine Galarza, Helay Hassas, Angie Upegui, David P. Greenberg, Corwin A. Robertson, Heather Entenmann, Evan Jones Mann, Liga Bennetts, Maureen P. Neary   +12 more
doaj   +1 more source

Current efforts towards safe and effective live attenuated vaccines against African swine fever: challenges and prospects [PDF]

, 2021
Tao Wang, Rui Luo, Yuan Sun, Hua‐Ji Qiu   +3 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Stimuli‐Responsive Biomaterials for Vaccines and Immunotherapeutic Applications [PDF]

, 2020
Noah Pacifici, Amir Bolandparvaz, Jamal S. Lewis   +2 more
openalex   +1 more source

The Safety of mRNA-1273, BNT162b2 and JNJ-78436735 COVID-19 Vaccines: Safety Monitoring for Adverse Events Using Real-World Data [PDF]

, 2022
Soonok Sa, Chae Won Lee, Sung Ryul Shim, Hyounggyoon Yoo, Jinwha Choi, Ju Hee Kim, Kiwon Lee, Myunghee Hong, Hyun Wook Han   +8 more
openalex   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

Advanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees, Maximilian Besenhard, Rawan Fitaihi, Hei Ming Kenneth Ho, Asterios Gavriilidis, Duncan Q. M. Craig   +5 more
wiley   +1 more source

Microbiome, sex hormones, and immune responses in the reproductive tract: Challenges for vaccine development against sexually transmitted infections

, 2013
Rebecca M. Brotman, Jacques Ravel, Patrik M. Bavoil, Patti E. Gravitt, Khalil G. Ghanem   +4 more
openalex   +1 more source