Results 41 to 50 of about 96,968 (259)
Viruses, 2014 Diagnostic electron microscopy for infectious diseases has the advantage that “everything” in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample.
Daniel R. Beniac +3 more
doaj +1 more source
When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond
Journal of Infection in Developing Countries, 2008 The presence of zoonotic poxviruses in nature represents a potential human health risk that has to be re-evaluated by health authorities not only in developing countries, but also in many developed countries.
Nissin Moussatché +2 more
doaj +3 more sources
Antiviral activity of the EB peptide against zoonotic poxviruses
Virology Journal, 2012 Background The EB peptide is a 20-mer that was previously shown to have broad spectrum in vitro activity against several unrelated viruses, including highly pathogenic avian influenza, herpes simplex virus type I, and vaccinia, the prototypic ...
Altmann Sharon E +3 more
doaj +1 more source
Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]
, 2011 VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward +1 more
core +1 more source
Clinical Infectious Diseases, 2003 The resumption of smallpox vaccination for health care workers and other first responders has raised concern about the occurrence of complications in people with immunodeficiency disorders, including those infected with human immunodeficiency virus.
Mike, Bray, Mary E, Wright
openaire +2 more sources
Smallpox Vaccination of Laboratory Workers at US Variola Testing Sites
Emerging Infectious Diseases, 2015 To evaluate the need to revaccinate laboratory workers against smallpox, we assessed regular revaccination at the US Laboratory Response Network’s variola testing sites by examining barriers to revaccination and the potential for persistence of immunity.
Sharon Medcalf +8 more
doaj +1 more source
Altered serological and cellular reactivity to H-2 antigens after target cell infection with vaccinia virus [PDF]
, 1975 MICE generate cytotoxic T lymphocytes (CTL) which are able to lyse virus infected target cells in vitro after infection with lymphocytic choriomeningitis virus (LCMV) and pox-viruses1−3.
BJ Alter +21 more
core +1 more source
The Rise and Fall of Modern Plagues
Molecular Frontiers Journal, 2020 Millennia separate smallpox, the oldest pandemic, and COVID-19, the newest. Both calamities arose from an opportunistic virus amid human crowding. A vaccine for smallpox existed since the late 18th century, but it took worldwide public health strategy to
G. Terry Sharrer
doaj +1 more source
Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion [PDF]
, 2005 Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription.
Dekker, Cees +5 more
core +2 more sources