Results 71 to 80 of about 98,253 (278)
Viruses, 2014 Diagnostic electron microscopy for infectious diseases has the advantage that “everything” in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample.
Daniel R. Beniac +3 more
doaj +1 more source
Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]
, 1985 We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A. +3 more
core
Vaccinia virus-based vector against infectious diseases and tumors
Human Vaccines & Immunotherapeutics, 2021 Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases.
Ziling Zhang +5 more
doaj +1 more source
Attenuation of Vaccinia Virus [PDF]
Acta Naturae, 2015 Since 1980, in the post-smallpox vaccination era the human population has become increasingly susceptible compared to a generation ago to not only the variola (smallpox) virus, but also other zoonotic orthopoxviruses. The need for safer vaccines against orthopoxviruses is even greater now.
YAKUBITSKIY S.N. +3 more
openaire +3 more sources
Mpox and the Ethics of Outbreak Management: Lessons for Future Public Health Crises
Developing World Bioethics, EarlyView.ABSTRACT Mpox, first identified in captive monkeys in 1958 and recognized in humans by 1970 in the Democratic Republic of Congo, was historically confined to sporadic zoonotic outbreaks in Central and West Africa. These outbreaks, often driven by rodent‐to‐human transmission in resource‐limited settings, reflect persistent systemic health disparities ...
Adetayo E. Obasa +3 more
wiley +1 more source
The viral protein VP6 of rotavirus coinmunoprecipated with HSC70 in cels MA104
Revista de la Facultad de Medicina, 2006 Introduction: Rotaviruses are the main cause of gastroenteritis in children under five years old. At this moment is unknown how these viruses entry to host cell. The heat shock cognate protein HSC70 has been involved in rotavirus cell entry. However, the
Luz Stella Rodríguez +1 more
doaj
Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines
Expert Review of Vaccines, 2018 Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the pressure to generate multi-valent and multi-pathogen vaccines grows.
Natalie A. Prow +4 more
doaj +1 more source
Smallpox Vaccination of Laboratory Workers at US Variola Testing Sites
Emerging Infectious Diseases, 2015 To evaluate the need to revaccinate laboratory workers against smallpox, we assessed regular revaccination at the US Laboratory Response Network’s variola testing sites by examining barriers to revaccination and the potential for persistence of immunity.
Sharon Medcalf +8 more
doaj +1 more source
Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]
, 1993 The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna +5 more
core +3 more sources
Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines
Immunology &Cell Biology, EarlyView.We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett +17 more
wiley +1 more source