Results 171 to 180 of about 1,158,425 (219)

Vaccinia virus morphogenesis and dissemination

Trends in Microbiology, 2008
Vaccinia virus is the smallpox vaccine. It is the most intensively studied poxvirus, and its study has provided important insights about virus replication in general and the interactions of viruses with the host cell and immune system. Here, the entry, morphogenesis and dissemination of vaccinia virus are considered.
Kim L, Roberts, Geoffrey L, Smith
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Vaccinia Virus Expression Vectors

Journal of General Virology, 1986
Introduction. Recombinant DNA technology has made possible the expression of heterologous genes in a variety of animal viruses (for review, see Rigby, 1983). The availability of a wide variety of animal virus vectors enables a foreign gene to be expressed in different cell types, at different levels and with different consequences for the host cell ...
M, Mackett, G L, Smith
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Vaccinia: Virus, Vector, Vaccine

1988
Publisher Summary This chapter discusses the genetic characterization of vaccinia, a general protocol for the insertion of foreign genes into vaccinia virus, and analysis of the recombinant viruses. The vaccinia virus can infect a variety of animals and is able to replicate in a variety of tissue culture cells. When experimenting with this virus, two
A, Piccini, E, Paoletti
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Topography of vaccinia virus DNA

Virology, 1977
Abstract Contour length measurements in an electron microscope of vaccinia genomes released from virions by lysis in Sarkosyl and 2-mercaptoethanol at 4° on the surface of gradients, followed by sedimentation into the gradients to remove proteins, showed that the linear, double-stranded (ds) viral DNA molecules prepared in this way, had a MW of 132 ...
M, Esteban, L, Flores, J A, Holowczak
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The wet preservation of vaccinia virus

Archiv f�r die gesamte Virusforschung, 1966
Buffered glycerol was shown to be an efficient preservation medium for vaccinia virus, but under the described experimental conditions it was not superior to serum, glycerol-serum, glycerol-broth or fortified Earle's saline in respect of preservative qualities, although it was in respect of its defined chemical composition.
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Vaccinia Virus as an Expression Vector

2003
Vaccinia virus (Vv) is a member of the genus Orthopoxvirus, one of seven genera included in the family Poxviridae. Most of these viruses infect vertebrates (Orthopoxvirus, Avipoxvirus, Capripoxvirus, Leporipoxvirus, Suipoxvirus, and Parapoxvirus), but one genus, Entomopoxvirus, infects insects.
A, Talavera, J M, Rodriguez
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The Insertion of DNA into Vaccinia Virus

Science, 1976
Cells infected with vaccinia virus in the presence of hydroxyurea (HU), which blocks DNA replication, were examined in thin sections by electron microscopy at intervals after removal of HU. Dense, fibrillar material was observed at the orifice formed just before closure of the membrane constituting the envelope of the immature form of the virus.
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The structure of vaccinia virus

The Journal of Pathology and Bacteriology, 1954
G, EAVES, T H, FLEWETT
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Radiation Inactivation of Vaccinia Virus

Radiation Research, 1961
Radiation inactivation of P/sup 3//sup 2/-labeled vaccinia virus indicates that the virus possesses one or two sites which are responsible for attachment to the host cell. The sensitive volume of the attachment site was found to correspond to a molecular weight of about 3 million.
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The Origins of Vaccinia Virus

Journal of Infectious Diseases, 1977
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