Results 41 to 50 of about 52,004 (230)

DNA Protection against Oxidative Damage Using the Hydroalcoholic Extract of Garcinia mangostana and Alpha‐Mangostin

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2016, Issue 1, 2016., 2016
Garcinia mangostana, popularly known as “mangosteen fruit,” originates from Southeast Asia and came to Brazil about 80 years ago where it mainly grows in the states of Pará and Bahia. Although mangosteen or its extracts have been used for ages in Asian folk medicine, data on its potential genotoxicity is missing.
Ronaldo Carvalho-Silva   +8 more
wiley   +1 more source

General measures in the treatment of sickle cell disease [PDF]

open access: yes, 2007
This article presents the most important measures in the care of patients with sickle cell disease, which is characterized by a high morbimortality rate.
Braga, Josefina Aparecida Pellegrini
core   +3 more sources

Emergence of Candida (Candidozyma) auris in Minas Gerais, Brazil: Genomic Surveillance to Guide Rapid Public Health Responses

open access: yesMycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé   +19 more
wiley   +1 more source

CD8+ T Cell‐Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?

open access: yesMediators of Inflammation, Volume 2014, Issue 1, 2014., 2014
MHC‐restricted CD8+ T cells are important during infection with the intracellular protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. Experimental studies performed in the past 25 years have elucidated a number of features related to the immune response mediated by these T cells, which are important for establishing the ...
Fernando dos Santos Virgilio   +6 more
wiley   +1 more source

Robust Immune Response and Protection against Lethal Pneumococcal Challenge with a Recombinant BCG-PspA-PdT Prime/Boost Scheme Administered to Neonatal Mice

open access: yesVaccines
Pneumococcal diseases are an important public health problem, with high mortality rates in young children. Although conjugated pneumococcal vaccines offer high protection against invasive pneumococcal diseases, this is restricted to vaccine serotypes ...
Monalisa Martins Trentini   +5 more
doaj   +1 more source

The Unexpected Actor? Civil‐Military Relations and Regulatory Agency Control in Brazil

open access: yesGovernance, Volume 39, Issue 1, January 2026.
ABSTRACT Democratic backsliding around the world has sparked debate about its impact on public administration and governance. This article explores a growing yet less visible phenomenon threatening democracy. It examines the influence exerted by authoritarian populists over autonomous regulatory agencies through militarized patronage, that is, the ...
Bruno Queiroz Cunha   +2 more
wiley   +1 more source

Induction of IL‐12 Production in Human Peripheral Monocytes by Trypanosoma cruzi Is Mediated by Glycosylphosphatidylinositol‐Anchored Mucin‐Like Glycoproteins and Potentiated by IFN‐γ and CD40‐CD40L Interactions

open access: yesMediators of Inflammation, Volume 2014, Issue 1, 2014., 2014
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), is characterized by immunopathology driven by IFN‐γ secreting Th1‐like T cells. T. cruzi has a thick coat of mucin‐like glycoproteins covering its surface, which plays an important role in parasite invasion and host immunomodulation. It has been extensively described that T.
Lúcia Cristina Jamli Abel   +8 more
wiley   +1 more source

Broad innate immune activation enhances the protective efficacy of rBCG-LTAK63 against Mycobacterium tuberculosis

open access: yesFrontiers in Immunology
IntroductionTuberculosis (TB) continues to be one of the leading infectious causes of mortality world-wide, while the Bacillus Calmette–Guérin (BCG) vaccine provides variable protection.
Ana Carolina de Oliveira Carvalho   +8 more
doaj   +1 more source

Chimeras could help in the fight against leptospirosis

open access: yeseLife, 2018
Understanding the structure of an antigen can guide the design of improved antigen-based vaccines.
Jademilson C Santos   +1 more
doaj   +1 more source

Vacinas em saúde pública [PDF]

open access: yesCadernos de Saúde Pública, 2020
Vaccines are one of the major triumphs of public health. What may sound like simple common sense has been reiterated in various articles in this Supplement of CSP. At this special moment of mobilization in the fight against the COVID-19 pandemic, the world is placing high expectations on the development of a SARS-CoV-2 vaccine, with many groups working
Luiz Antonio Bastos Camacho   +1 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy