Results 101 to 110 of about 437,206 (353)

Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement

Advanced Science, EarlyView.
This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang, Mei Qing, Haobo Xu, Jinbao Tao, Fangman Li, Pingfei Ge, Yang Yang, Wenqian Wang, Yongen Lu, Donald Grierson, Zhibiao Ye, Yuyang Zhang   +11 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Lipid synthesis and membrane contact sites: a crossroads for cellular physiology

Journal of Lipid Research, 2016
Membrane contact sites (MCSs) are regions of close apposition between different organelles that contribute to the functional integration of compartmentalized cellular processes.
J.Pedro Fernández-Murray, Christopher R. McMaster   +1 more
doaj   +1 more source

Absorption and Screening in Phycomyces [PDF]

, 1967
In vivo absorption measurements were made through the photosensitive zones of Phycomyces sporangiophores and absorption spectra are presented for various growth media and for wavelengths between 400 and 580 mµ.
Burke, Patricia V., Delbrück, M., Zankel, K. L.   +2 more
core   +2 more sources

Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]

, 2014
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T., Louis C., Matsumoto A., Matsumoto A., Newhall W.J., Scidmore M.A., Ward M.E.   +6 more
core   +1 more source

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

Advanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan, Shumin Zhou, Jiaming Zhou, Guanghui Zhang, Jingshou Chen, Rui Liu, Kuan Sun, Sisi Li, Wenjing Xiong, Yujiao Wen, Jianzhong Sheng, Yu Zhang, Jingchao Ren, Youjiang Li, Hefeng Huang, Chen Zhang   +15 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Multinodular and Vacuolating Neuronal Tumor

Open Access Macedonian Journal of Medical Sciences, 2018
BACKGROUND: Multinodular and Vacuolating Neuronal Tumor (MVNT) of the cerebrum is a benign lesion described recently in the WHO CNS tumours in 2016. Although this tumour is uncommon, clinicians should be acquainted with the possible presentation and imaging findings.
Zahra, Charmaine, Grech, Reuben
openaire   +5 more sources

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

Identification of vacuole defects in fungi

Journal of Microbiological Methods, 2012
Fungal vacuoles are involved in a diverse range of cellular functions, participating in cellular homeostasis, degradation of intracellular components, and storage of ions and molecules. In recent years there has been a significant increase in the number of studies linking these organelles with the regulation of growth and control of cellular morphology,
Richards, A., Gow, N.A.R., Veses, V.
openaire   +4 more sources